Some phytochemical work -
Alkaloids from Trachelospermum jasminoides, Atta-ur-Rahman et al., Planta Medica, 54(4):364, 1988.
The authors have found that Ibogaine is present, along with tabernaemontanine, vobasine and voacangine-7-hydroxyindolenine.
The authors do not indicate the percentage of alkaloids.
Below are some excerpts.
"From the leaves and stems of Trachelospermum jasminoides Lem (Apocynaceae) (1), four indole alkaloids, namely ibogaine, tabernaemontanine, vobasine, and voacangine-7-hydroxyindolenine, have been isolated. [...]"
"Leaves and stems (50 kg) were dried in the shade and extracted with ethanol. The crude alcoholic extracts were concentrated and partitioned between 10% hydrochloric acid and chloroform (pH 1). The chloroform layer was dried with anhydrous sodium sulfate and concentrated to a gum (25 g, F1). The aqueous acidic layer was basified with aqueous ammonia and extracted into chloroform at various pH values (5, 7, 9, and 11). The fraction obtained at pH-5 (20 g, F2) was found to contain major alkaloids. We have recently reported five indole alkaloids from this plant (2)."
"The crude alkaloidal fraction (F1, 25 g) was subjected to flash chromatography. [...] The alkaloid isolated was identified as voacangine-7-hydroxyindolenine by comparison of its spectral data with those reported in the literature (3). [...] Voacangine-7-hydroxyindolenine may have been formed by air oxidation during the extraction and isolation process."
"Fraction F2 (20 g) was also loaded on a silica column (750 g) and was eluted with increasing polarities of mixtures of petroleum ether, chloroform, ethyl acetate, and methanol."
"The fraction obtained on elution with chloroform:ethyl acetate (3:1) consisted of a mixture of four alkaloids. This fraction was subjected to a flash chromatography which was eluted with increasing polarities of mixtures of petroleum ether in acetone. The fraction obtained on elution with 70% petroleum ether in acetone was found to contain two major alkaloids. These alkaloids were separated by preparative TLC on silica gel (petroleum ether:acetone:ammonia, 6:3.95:0.05). The faster moving alkaloid was identified as ibogaine by comparison of its spectral data with those reported in the literature (7) while the slower moving alkaloid was identified as tabernaemontanine (8)."
"Further elution of the same column with 60% petroleum ether in acetone afforded another alkaloid which was further purified by preparative TLC on silica gel (petroleum ether:acetone:ammonia, 1:1:0.02). This alkaloid exhibited spectral data identical to those of vobasine (9)."
"(1) Perry, Z. M. (1895) Medicinal Plants of East and South East Asia, 31, MIT Press, Cambridge."
"(2) Rahman, A. U., Fatima, T., Nisa, M., Wasti, S., Cranck, G. (1987) Planta Med. 53, 57."
"(3) Agwada, V. C., Morita, Y., Renner, U., Hesse, M., Schmid, H. (1975) Helv. Chim. Acta 58, 1001."
[...]
"(7) Biemann, K., Friedmann-Spiteller, M. (1961) J. Am. Chem. Soc. 83, 4805."
"(8) Husson, A., Lauglois, Y., Riche, C., Husson, H. P., and Potier, P. (1973) Tetrahedron 29, 3095."
"(9) Renner, U., Prins, D. A., Burlingame, A. L., Biemann, K. (1963) Helv. Chim. Acta 46, 2186."
A little info here, from a review of the Voacanga genus, on tabernaemontanine and vobasine, the other alkaloids reported.
"Dregamine (a stereo-isomer of tabernaemontanine)has convulsant and respiratory-stimulant properties and is said to inhibit fatigue; it antagonizes prochlorperazine (but not reserpine) catalepsy, and , like vobasine, when administered together with Rigidyl (diethylaminoethyl benz-hydryl ether hydrochloride) causes head shaking in mice.
Tabernaemontanine causes peripheral vasodilation in chloralised dogs; it is claimed to be of use when given orally in certain geriatric conditions (arteriosclerosis, cerebral trauma (headache, vertigo, memory difficulties, etc), peripheral circulatory irregularities). The mixture of the hydrochloride salt with those of vobasine and ochropamine is stated to have anti-inflammatory, ant-pyretic and analgesic activity compareable with that of acetylsalicyclic acid but longer lasting. Vobasine on it's own has little or no anti-inflammatory activity and its antipyretic and analgesic actions are at best modest. High doses of the alkaloid give rise to central (including respiratory) depression; the autonomous nervous system is not affected. The compound has no diuretic activity. Perivine, tabernaemontanine and vobasine appear to be devoid of antiviral and anticancer activity."