In this study leaves and bark of different Australian specimens were quantitavely and qualitatively analysed for their alkaloids.
In the leaves the alkaloids isolated,at about 0.22% yield, were ibogaine, iboxygaine, ervatamine, 19-dehydroervatamine and apparacine. in the ratios of 1.8 : 0.25 : 0.5 : 1 : 2 respectively.
Three samples of bark were found to contain 1.3 %, 2 % and 1.4 % alkaloids. The alkaloids were found to be a mixture of ervatamine, tabernaemontanine, 16-demethoxycarbonyl-20’-epidihydro-voacamine, 20-epiervatamine, dregamine, 19-dehydroervatamine, vobasine, voacamine, 16-demethoxycarbonyl-dihydro-voacamine and voacristine.
The following alkaloids are of the ibogan type, ibogaine, iboxygaine and voacristine.
The alkaloids voacamine, 16-decarbomethoxy-19,20-dihydrovoacamine and 16 decarbomethoxy-19,20-dihydro-20-epi-voacamine are actually dimeric alkaloids constructed from a single ibogaine molecule combined with either a dregamine or tabernaemontanine molecule.