Tetrahydroharmine

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Tetrahydroharmine
2D diagram of the chemical structure of tetrahydroharmine
Identifiers
Abbreviations THH
CAS number 17019-01-1 7pxN
PubChem 159809
ChemSpider 140510 7pxY
KEGG C09243 7pxY
MeSH Tetrahydroharmine
ChEBI CHEBI:311931 7pxY
ChEMBL CHEMBL129208 7pxY
3DMet B02865
Jmol-3D images Image 1
Properties
Molecular formula C
13
H
16
N
2
O
Molar mass 216.279 g/mol
Boiling point 399.2°C
Basicity (pKb) 10.334
Hazards
Flash point 195.2 °C (383.4 °F; 468.3 K)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Tetrahydroharmine (THH) is a fluorescent indole alkaloid that occurs in the tropical liana species Banisteriopsis caapi.[1] THH weakly inhibits serotonin reuptake.[2]

Two other harmala alkaloids in B. caapi, harmaline and harmine, are reversible inhibitors of monoamine oxidase A. Tetrahydroharmine, however, does not inhibit monoamine oxidase A.

See also

References

  1. Callaway, James C. (June 2005). "Various alkaloid profiles in decoctions of Banisteriopsis caapi". Journal of Psychoactive Drugs 37 (2): 151–5. ISSN 0279-1072. PMID 16149328. doi:10.1080/02791072.2005.10399796. Retrieved 2012-08-10. 
  2. Callaway, James C.; McKenna, Dennis; Grob, Charles S.; et al. (June 1999). "Pharmacokinetics of hoasca alkaloids in healthy humans". Journal of Ethnopharmacology 65 (3): 243–56. ISSN 0279-1072. PMID 10404423. doi:10.1016/S0378-8741(98)00168-8. 

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