Phosphoramidon

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Not to be confused with phosphamidon.
Phosphoramidon
Phosphoramidon.png
Identifiers
CAS number 36357-77-4 YesY
PubChem 445114
ChEMBL CHEMBL479579 N
Jmol-3D images Image 1
Properties
Molecular formula C23H34N3O10P
Molar mass Script error g mol−1
Appearance White to slightly yellow solid
Solubility in water Soluble as sodium salt[1]
Solubility in DMSO and methanol Soluble as sodium salt[1]
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N (verify) (what is: YesY/N?)
Infobox references

Phosphoramidon is a chemical compound derived from cultures of Streptomyces tanashiensis. It is an inhibitor of the enzyme thermolysin,[2] a membrane metallo-endopeptidase inhibitor,[3] and an endothelin converting enzyme inhibitor.[3] Chemically, talopeptin differs from its closely related peptidase inhibitor talopeptin by a single stereocenter.

Because of its enzyme inhibitory properties, phosphoramidon is widely used as a biochemical tool.

References

  1. 1.0 1.1 Phosphoramidon, Enzo Life Sciences
  2. Kitagishi K; Hiromi K (1984). "Binding between thermolysin and its specific inhibitor, phosphoramidon". Journal of Biochemistry 95 (2): 529–34. PMID 6715312. 
  3. 3.0 3.1 Phosphoramidon at PubChem

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