JWH-030

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JWH-030
JWH-030.svg
Systematic (IUPAC) name
naphthalen-1-yl-(1-pentylpyrrol- 3-yl)methanone
Clinical data
Legal status ?
Identifiers
CAS number 162934-73-8 7pxY
ATC code ?
PubChem CID 9971539
ChemSpider 8147131
Chemical data
Formula C20H21NO 
Mol. mass 291.386 g/mol
 14pxY (what is this?)  (verify)

JWH-030 is a research chemical which is a cannabinoid receptor agonist.[1] It has analgesic effects and is used in scientific research.[2] It is a partial agonist at CB1 receptors, with a Ki of 87nM, making it roughly half the potency of THC.[3] It was discovered and named after Dr. John W. Huffman.

See also

References

  1. Lainton JAH, Huffman JW, Martin BR, Compton DR. Tetrahedron Letters. 1995; 36:1401.
  2. Pertwee RG, Griffin, G, Lainton JAH, Huffman JW. European Journal of Pharmacology. 1995; 284:241.
  3. Griffin, G.; Atkinson, P. J.; Showalter, V. M.; Martin, B. R.; Abood, M. E. (1998). "Evaluation of cannabinoid receptor agonists and antagonists using the guanosine-5'-O-(3-35Sthio)-triphosphate binding assay in rat cerebellar membranes". The Journal of Pharmacology and Experimental Therapeutics 285 (2): 553–560. PMID 9580597.  edit
      
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