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Gigantine is an isoquinoline alkaloid found in Carnegiea gigantea and other related cacti. Gigantine was first discovered along with Macromerine in 1967.  i It is found in significant quantities in many mescaline-containing cactus species, but it is unclear whether gigantine contributes in any way to their psychoactive effects.
- Bruhn JG, Lundström J (1976). "Alkaloids of Carnegiea gigantea. Arizonine, a new tetrahydroisoquinoline alkaloid". Lloydia 39 (4): 197–203. PMID 957908.
- "Two New Alkaloids in Cacti" [macromerine and gigantine] J E Hodgkins, Tet. Lett., 14, 1321 (1967)
- Shulgin AT, Perry WE. The Simple Plant Isoquinolines. Transform Press, 2002. ISBN 978-0-9630096-2-3