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Pentobarbital

5-ethyl-5-(1-methylbutyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione; 5-Ethyl-5-(1-methylbutyl)barbituric acid, C11H18N2O3 (mol. wt. 226.27)

Nembutal, prescription sedative hypnotic

CAS76-74-4

Dosage:

  • IM Injection

    For trouble in sleeping:
    Adults--150 to 200 mg, injected into a muscle.
    Children--Dose is based on body weight and must be determined by your doctor. The usual dose is 2 to 6 mg per kg (0.9 to 2.7 mg per pound) of body weight, injected into a muscle.

    For sedation before surgery:
    Adults--150 to 200 mg, injected into a muscle.
    Children--Dose is based on body weight and must be determined by your doctor. The usual dose is 2 to 6 mg per kg (0.9 to 2.7 mg per pound) of body weight, injected into a muscle. However, the dose is usually not more than 100 mg.

    For control of seizures:
    Children--At first, 50 mg injected into a muscle or vein. Additional small doses may be given if needed.

  • IV Injection

    For trouble in sleeping:
    Adults--100 mg injected into a vein, with additional small doses given if needed. However, the dose is usually not more than 500 mg.
    Children--Dose is based on body weight and must be determined by your doctor. The usual dose is 50 mg injected into a vein, with additional small doses given if needed.

    For control of seizures:
    Adults--At first, 100 mg injected into a vein. Additional small doses may be given if needed. However, the dose is usually not more than 500 mg.
    Children--At first, 50 mg injected into a muscle or vein. Additional small doses may be given if needed.

  • Oral

    For trouble in sleeping:
    Adults--100 milligrams (mg) at bedtime.
    Children--Dose must be determined by your doctor.

    For daytime sedation:
    Adults--20 mg three or four times a day.
    Children--Dose is based on body weight and must be determined by your doctor. The usual dose is 2 to 6 mg per kilogram (kg) (0.9 to 2.7 mg per pound) of body weight per day.

    For sedation before surgery:
    Adults--100 mg before surgery.
    Children--Dose is based on body weight and must be determined by your doctor. The usual dose is 2 to 6 mg per kilogram (0.9 to 2.7 mg per pound) of body weight, taken before surgery. However, the dose is usually not more than 100 mg.

  • Rectal

    For trouble in sleeping:
    Adults--120 to 200 mg inserted into the rectum at bedtime.
    Children up to 2 months of age--Dose must be determined by your doctor.
    Children 2 months to 1 year of age--30 mg inserted into the rectum at bedtime.
    Children 1 to 4 years of age--30 or 60 mg inserted into the rectum at bedtime.
    Children 5 to 12 years of age--60 mg inserted into the rectum at bedtime.
    Children 12 to 14 years of age--60 or 120 mg inserted into the rectum at bedtime.

    For daytime sedation:
    Adults--30 mg inserted into the rectum two to four times a day.
    Children--Dose is based on body weight or size and must be determined by your doctor. The usual dose is 2 mg per kg (0.9 mg per pound) of body weight, inserted into the rectum three times a day.

    For sedation before surgery:
    Children up to 2 months of age--Dose must be determined by your doctor.
    Children 2 months to 1 year of age--30 mg inserted into the rectum.
    Children 1 to 4 years of age--30 or 60 mg inserted into the rectum.
    Children 5 to 12 years of age--60 mg inserted into the rectum.
    Children 12 to 14 years of age--60 or 120 mg inserted into the rectum.


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Created 3/24/2000 1:08:33
Modified 1/2/2001 19:26:33
Leda version 1.4.3