2C-B and Related Substances info

More than a compilation of 2cb related info from different sources, but labeled as a FAQ

2C-B... is a tool... which ties the mental processes directly and constructively into the physical soma. The analgesic effects experienced with many, if not most, psychedelic drugs, are not present with 2C-B. On the contrary, there is increased body awareness of every kind, including skin sensitivity, heightened responsiveness to smells, tastes, and sexual stimulation. One experiences increased consciousness of physical health and energy, or, on the other hand, sharpened awareness of any body imbalance or discomfort. 2C-B allows for rich visual imagery and intesnse eyes- closed fantasy without the cluttering up of the mental field with too much elaboration... It is a superb tool for learning and growth.

MDA:
MDMA:

amphetamine:

And just for kicks here we have good old LSD which looks nothing like all these other chemicals:

From: cutrell@nic.cerf.net (Doug Cutrell)
Date: 8 Jul 92 23:31:16 GMT
Newsgroups: alt.drugs
Subject: Re: LSD.

Lamont Granquist writes:
DOB has a potency of 1.0-3.0 mg and duration of 18-30 hours. Its very similar to LSD. It seems to be more colorful than LSD and less dissociative than 2C-B based on the reports I've read. The index of safety is probably something like over 1,000 times the effective dose.

This figure is probably based on animal experiments described by Shulgin in Pihkal. However, he goes on to say that the index of safety is probably much lower than this. He says there are numerous reports of overdoses causing vascular arterial spasm, and gives one verified account of a couple who thought they had MDA and took quantities appropriate for that compound... i.e. around 100 mg. The woman died, the man lived after convulsions and a week in a coma. Since the standard dose is 1-3 mg., the lethal dose is more like 30 times the effective dose.

Doug Cutrell
cutrell@cerf.net




Well, in a thread recently, there was some talk aabout bromo mescaline, and mention was made of the entry in the Student Handbook of our esteemed institution that deals with the drug in question. Well, it is Reed folklore that tells us that bromo mescaline was first synthesized here at Reed (BTW, it is not folklore that Dr. Demento graduated from Reed), but the drug is real, to which several friends can attest. Since I have the ol' Student Handbook right in front of me, I'll tell y'all what it sez.

From _The Reed College Student Handbook_, in the "Drug Article That Ate Reed College", by Marty Smith:

Bromo-mescaline. The most terrifying hallucinogen known to man. The effects last 3-5 hours, the visuals are awe-inspiring and the head trip is light, usually. The catch is, first, for it to act like bromo, you have to snort it. This is really intense, because in about two to five minutes, you're tripping you ass off, the world is melting. The incredible speed with which this happens is one of the things those who like it like about it. However, when it gets up your nose it hurts. This is probably an understatement. It's really amazingly painful. You'll be suprised that you would actually do this to yourself. It has been described as having red hot knives shoved up your nose, or being kicked in the face by a psychedelic horse. You may briefly entertain notions of dying. This all dies down after about twenty minutes, though, and you're lucky there will be no nausea at all afterward. (It helps to have eaten a starchy meal about an hour and a half earlier.) Otherwise, you might have about 20 minutes of mild nausea. The visuals are real good. To have visuals this intense on acid you'd have to be on so much that you couldn't talk. On bromo you could discuss them reasonably coherently.

A word about dosage. One hit is one fourtieth of a gram. This is a fact. Do not say something stupid like, "Oh, let's do a lot," and hoot up a couple of lines the size of your thumb. I have some friends who did this, and they ended up lying under some bushes, at night, in the rain, unable even to yell for help, and now they will not do drugs for the next five million jillion years.

--------------------------------------------------------------------------- That's the straight dope (none of the many puns intended).

late,
miguel


pierre@media.mit.edu (Pierre St. Hilaire) writes:
Sure. And table salt releases sodium and chlorine in your body, so you will both catch fire and suffocate if you take it. Adding halogen atoms to psychedelic amines can significantly modify their potency, duration, and effects. Read Alexander Shulgin's PIKHAL for an extensive discussions on halogenated substituted phenylethylamines.

yes, i believe that "bromomescaline" 2-CB aka CBr... 2,5-dimethoxy-4- bromophenethylamine. the reason why it probably burns going up your nose is that it may lack any kind of anaesthetic action (unlike MDA, MDMA, and particularly cocaine), while still being in the form (probably) of a hydrochloric salt (where the HCl comes from).

culled from the MDMA FAQ: CBr is 2,5-Dimethoxy-4-Bromophenethylamine. The "sometimes frightening" part probably comes from taking more than the full dose, and the literature suggests that with larger dosages come disproportionately larger responses, unlike some other psychedelics we all know and love. I've had very enlightening experiences with CBr, and they grew better in quantum leap fashion. + wonderful and gently insightful (semi-wilderness, daytime, friends).
+ profoundly sexual with glimpses of bird-animal forms (indoors, nightime, lover) minor telepathic imagery.
+ sexual and shamanic, native american imagery (indoors, day-night, alone).
+ profound native american imagery (indoors, night, after cannabis, friend) actually slept a bit (too much cannabis) and awoke to the most wonderful visuals (friend in other room - ditto).
+ full-blown spirit animals all night long (desert, night, friend, good THC 1/2 way thru trip) - mountain lion (very playful) and eagle most prominent two deer (incredibly loving), a wolf (very brief), fantastic living plant spirits, entities in mountain, mucho native american imagery, et. al. very telepathic with friend. brief teleportation/desert-zoom experience. understood the ancients' fascination with constellations. imparted with sudden knowledge in extreme detail - confirmed later by ex-lover, scared ex-lover shitless.

My last experience with CBr changed my life in many profound ways (for the better). With THC and a little concentration I can get back to some of those places. With no THC and a lot of concentration I can get back to some of those places. Remember.

I believe CBr is recognized as an enthogen and an entactogen, and unfortunately it's now Schedule 1. :-( Put this one on the top of the list of drugs to be legalized.


Date: Sun, 28 Feb 1993 00:22:14 -0800
From: Alexander T. Shulgin
To: lamont@hyperreal.com
Subject: bromo

Hi:

There has been quite a flow of stuff on the subject of BROMO on alt.drugs entry. Maybe you can post some parts of the following that might answer some of the comments, questions, or errors being put out there on the topic.

(1) Bromomescaline is without doubt 2C-B. The dosage, the duration, the nature of the experience, all seem consistent with this assignment. Also, as you have indicated, the replacement of a methoxy group (of mescaline) with a bromo atom gives the isomeric structure (a little rearrangement needed) of 2C-B.

(2) It releases bromic acid. Of course not. Bromic acid (HBrO3) is an unstable chimera which is substantially unknown. Probably what is meant is that it releases hydrobromic acid (HBr) but then there is no experimental evidence that HBr is released either. I suspect that the bromine atom stays on the drug molecule all the way through the kidney, and that there is no release of this element at any time in the body.

(3) It is illegal, or a scheduled drug. No so. 2C-B was added to the German law in January of this year, but in the US it is still an unnamed drug in Federal law.

(4) It burns on snorting (insufflation). It sure does, but this is most likely due to the fact that it is extremely insoluble in water, and probably sits on the mucous membranes for quite a while until it dissolves and is absorbed. And until this happens it irritates and blisters the skin at the sites where the solid particles of the drug happen to settle. Once absorbed, the pain disappears, and the effects start. A challenge to this would be to snort the acetate or the hydrobromide salt, both of which are quite a bit more soluble in water. These should have the same psychological effect, and they should act even more quickly (no slow dissolving) and act with little or no pain.

I would love to know who in the wide wide world of information input discovered the term bromic!! It cannot believe it has any merit.

Can you drift some of this on to the world of alt.drugs and satisfy this search for information?

Thanks.

Sasha


From: Mark_Farone@sfa.ufl.edu (Mark Farone)
Newsgroups: alt.psychoactives
Subject: Re: 2C
Date: 18 Apr 1994 12:28:10 GMT
Message-ID: <Mark_Farone-180494082742@128.227.37.18>
In article <766538637-0-4072@chop.isca.uiowa.edu>, David Roknich <Hologram@chop.isca.uiowa.edu> wrote:

• dg596@cleveland.Freenet.Edu (Russell Faraday)writes: Another new sensation gripping our little pocket of cultural coolness is something called 2CB. As a discussion starter, I'd ...... 2CB is a designer drug that was not illegal until a few morons blathered publicly about its existance in the early 80s
  
  With respect to US laws, 2cb (aka Nexus, Zenith) wasn't scheduled until late 1993.
  Its actual chemical name is 4-Bromo-2,5-Dimethoxyphenethylamine.
  
  The Feds were alerted when a rather rich fella in Tampa, FL took some to relieve impotence, as it was being promoted. When started tripping he called the DEA and the next thing you know...
  
  See _Federal Register_, Vol. 58, No. 212, Thurs. Nov 4,1993 page 58819-20.
  
  

  _________________________________________________________________________
  Mark Farone               "A pile of rocks ceases to be a rock pile when
  University of Florida         somebody comtemplates it with the idea 
  Mark_Farone@sfa.ufl.edu          of a cathedral in mind." -Saint Exupery
  

  
  
  
  From: bgg@connect.com.au (Ben Golding)
  Newsgroups: alt.drugs
  Subject: 2CB report from Sydney Morning Herald (18 May 94)
  Date: 20 May 1994 11:34:39 +1000
  Message-ID: <2rh43f$81k@warrane.connect.com.au>
  
  A wonderfully fact-free article from the SMH.
  
  Operation Noah is an annual campaign where people are encouraged to call the police to dob in a drug users and suppliers. Over the years it has been running it has been steadily galvanising public opinion against the operation and pushing discussion of drug policy to the fore. As you can imagine, most of the busts are people with a plant in their backyard with neighbours who don't like them, you know, exactly the sort of people that pose the greatest threat to society.
  
  Ben.
  
  Noah Hunts New Drug, Emma Tom, Sydney Morning Herald, Wed.18th, 1994
  
  A dangerous new designer drug similar to ecstasy is among the amphetamines to be targeted today in operation Noah, the annual national drugs phone-in.
  Detective Sergeant Mal Brammer, from the NSW Drug Enforcement Agency, said the new drug, known as nexus or 2CD (sic), had originated at dance parties in the United States.
  He said nexus differed from ecstasy in that it was stronger, lasted longer and caused hallucinations. Part of its attraction was that it "temporarily alleviated impotency and frigidity".
  "We are concerned that nexus is being mixed with or sold as ecstasy," he said.
  
  
  From: bgg@connect.com.au (Ben Golding)
  Newsgroups: alt.drugs
  Subject: Re: 2CB report from Sydney Morning Herald (18 May 94)
  Date: 21 May 1994 12:56:56 +1000
  Message-ID: <2rjt9o$ip6@warrane.connect.com.au>
  
  [quoted text deleted -cak]
  
  Further to this article, Here's a response to the letters page:
  
  Re: "Noah hunts new drug", Emma Tom, April 18th 1994, p.10
  
  Before we panic about a new designer amphetamine, which Nexus is not, I feel some clarification is in order. I am a medicinal chemist in regular contact with Dr. Alexander Shulgin, who has devoted his life to producing new drugs for use in therapy, and names 2C-B (not 2CD) as his greatest discovery. Not originating at dance parties, it has been known to the scientific community for years. Concerning legality: the NSW poisons list prohibits chemicals of its class with hallucinogenic properties. 2C-B is unlisted, and its hallucinogenic properties debatable . It does not cause true hallucinations but visual distortions at high do ses, and is subjectively different from other drugs such as ecstasy. It is not a stimulant, and lacks side-effects such as overheating and post-use fatigue. Unlike LSD it leaves the user mentally clear and lucid, and so is unlikely to cause a panic reaction. As for dangerous, 2C-B is essentially non-addictive, rel atively short acting, has no known serious side-effects, and no recorded overdose cases. Legal or illegal, like it or not, it will probably be increasingly popular.
  
  
  Newsgroups: alt.drugs
  From: bprofane@netcom.com (Gert Niewahr)
  Subject: Re: long term effects of 2cb?
  Message-ID: <bprofaneCDDz5x.yJ@netcom.com>
  Date: Wed, 15 Sep 1993 08:20:20 GMT
  
  In article <2735jl$kcj@agate.berkeley.edu> bbehlen@soda.berkeley.edu (Brian Behlendorf) writes:
  After peusing the various net.resources on the subject, as well as checking PiHKAL, I haven't been able to find any info on possible long-term effects of 2CB. Anyone have any recent info on this? I suppose I could ask Shulgin, since he's teaching a class here at Cal.... If you mean 2C-B toxicity tests equivalent to those done for MDMA (Ecstacy), no, I haven't heard of any. Those neurotransmitter degradation tests filtered out to the net pretty quickly too, so I'd be half surprised if a 2C-B evaluation was underway that we haven't heard about.
  
  I'd offer the same lay demographic survey I described at length a few years ago to rebut the MDMA toxicity tests: As an undergraduate, I was part of what was effectively a test group of 18-21 year-old college students regularly consuming very pure phenethylamines (mainly MDMA and 2C-B). This group was large enough to be statistically stable (500+ subjects) yet so homongenous in terms of intelligence, motivation, education, and background as to form a narrow behavioral profile. Moreover, this group was complemented by an otherwise identical control group of about 700 subjects. Both groups can be characterized as highly intelligent (having had to score in the top 5th percentile of most standardized tests in order to be part of either group) and destined for careers demanding high intellectual ability.
  
  As I noted a few years back, the differentiation between these two groups is effectively zilch. The most significant statistic characterizing samples of this type of subject (i.e., graduates of this college) is that about one in five attains a PhD, the highest percentage for non-science universities in the US. Almost half finish some kind of graduate degree. It's a little early, even after ten years, to evaluate whether these groups have or will attain the norms, but it looks like both are on track. In fact, the per capita numbers are climbing a little. Unless the puritans are working overtime to make up for the druggies, both parties are on the beam.
  
  But, as I say, the differentiation is nil. I knew a large percentage of both groups personally, and as I look over the class notes, knowing who did what, I see no sign that the two groups are diverging in terms of the gross career achievement profile. Lots of lawyers and MDs on both sides of the fence. Lots of papers being published by grads of both stripes. In fact, some of the most notorious drug chemists (who cooked up most of the X and bromo we all ingested) are post-docs or teaching faculty already. (Yes, that bright young assistant prof. teaching organic may have been whipping up job lots of X not that long ago.)
  
  Yes, this is a very rough demographic analysis. I can't hand out questionaires about past drug use and current grad school at reunions. But I'm also close enough to feel empirically confident about the profiles, and I've seen serious studies published that relied on smaller and more dubious samples that this.
  
  Oh, I should make it clear, in light of Brian's question, that about 35-40% of the phenethylamines ingested were 2C-B, by my estimation. That's a lot, given the per capita volume. It was quite easy to score 5-10 grams a pop.