- 2C-B (4-bromo-2,5-dimethoxyphenethylamine)
- 2C-T-7 (4-propylthio-2,5-dimethoxyphenethylamine)
- 5-MeO-DIPT (5-methoxy-N,N-diisopropyltryptamine)
- Amphetamine (a-methylphenethylamine)
- Caffeine (1,3,7-trimethylxanthine)
The most popular psychoactive drug in the world. Use of this stimulant is encouraged in most workplaces, although it can be physically addictive.
- Cocaine (Methylbenzoylecgonine)
- DMT (N,N-dimethyltryptamine)
- DXM (dextromethorphan)
Cough-suppressing agent found in many over-the-counter cough and cold remedies; Dissociative at higher doses
- Ethanol (Ethyl Alcohol)
- GHB (g-hydroxybutyrate)
Sedative closely related in structure to GABA. Now a schedule I substance in the USA.
- Heroin (diacetylmorphine)
- Ketamine (2-(2-chlorophenyl1)-(methylamino)-cyclohexanone hydrochloride)
Ketamine is used as a veterinary and medical anaesthetic, and has dissociative/psychedelic effects at lower doses.
- LSA (D-lysergic acid amide)
- LSD (D-lysergic acid diethylamide)
One of the most potent psychoactive drugs known, LSD is the prototypical psychedelic. Tihkal #26
- MDMA (3,4-methylenedioxy-N-methylamphetamine)
- Mescaline (3,4,5-trimethoxyphenethylamine)
- Methamphetamine (N-methylamphetamine)
- Nitrous oxide ("Laughing Gas")
When inhaled, this gas acts as a dissociative anaesthetic. In addition to its ludible uses, it is a dental anaesthetic and is used industrially.
Most potent naturally-occuring entheogenic chemical yet discovered; Active constituent of Salvia divinorum
- THC (Tetrahydrocannabinol; delta-9-tetrahydrocannabinol; delta-1-tetrahydrocannabinol)
Primary chemical responsible for the psychoactive effects of cannabis.
- Alkyl nitrites ("Poppers")
- Amphetamines, Analogs, and Precursors (Amphetamine and its stimulant analogs, as well as synthetic precursors.)
- Ergolines (Includes LSD and LSA)
- Ethers (Class of organic compounds in which two hydrocarbon groups are linked by an oxygen atom)
- GHB-related (Chemicals which are structurally similar to GHB and GBL)
- Phenethylamines (Includes mescaline, MDMA, amphetamines, and precursors.)
- Psychedelic Amphetamines (Includes MDMA, DOB, DOM, TMA-2 and many others described in PIHKAL)
- Tryptamines (Prototypical indole family including serotonin and such psychedelic drugs as DMT and psilocybin.)
View all 54 Chemical Families
View all 492 Chemicals