Chemicals

• Alkyl compounds (Hydrocarbons and derivatives, fumes are sometimes inhaled)
  • Alcohols (Oxygen bonded with hydrogen and an alkyl group)
    • Cyclohexanols
      • Menthol (Cyclohexanol)
        Strong minty taste; Toxic
      • Tramadol
        "Ultram". Prescription non-opioid analgesic.
    • Chloral hydrate (Trichloroacetaldehyde Monohydrate; Aquachloral; Novo-Chlorhydrate)
      A sedative-hypnotic sometimes used before surgery or certain procedures to relieve anxiety or tension or to produce sleep.
    • Ethanol (Ethyl Alcohol)
    • Ethchlorvynol (Ethyl 2-chlorovinyl ethynyl carbinol; "Placidyl")
    • Trichloroethanol (2,2,2-trichloroethanol)
      Active metabolite of chloral hydrate.
  • Alkyl nitrites ("Poppers")
    • Amyl nitrite (Pentyl Alcohol Nitrite; Nitrous acid, pentyl ester; n-amyl nitrite; nitramyl)
    • Butyl nitrite (n-Butyl nitrite)
  • Ethers (Class of organic compounds in which two hydrocarbon groups are linked by an oxygen atom)
    • Ether (ethyl ether; diethyl ether)
    • Isoflurane (1-Chloro-2,2,2-Trifluoroethyl Difluoromethyl Ether)
  • Halogenated Hydrocarbons
    • Chlorinated Hydrocarbons
      • Chloroform (Trichloromethane; Methyl trichloride)
      • Dichloromethane (DCM; Methylene (di)chloride)
        A nonpolar solvent often used in plant extractions
      • Ethyl Chloride (monochloroethane; hydrochloric ether; Muriatic Ether; Chloroethane)
        Anesthetic used recreationally as an inhalant
      • Trichloroethylene
    • Halothane (2-Bromo-2-Chloro-1,1,1-Trifluoro-ethane)
• Antidepressants
  • Citalopram
    Antidepressant marketed as "Celexa"
  • Fluoxetine
    "Prozac"
  • Sertraline (1-Naphthylamine)
    "Zoloft"
• Arylcyclohexylamines (Includes several dissociative drugs, including Ketamine and PCP)
  • Cyclohexamine (Eticyclidine)
  • Dizocilpine ((+)-10,11-dihydro-5-methyl-5H-Dibenzo[a,d]cyclohepten-5,10-imine)
    Also known as "MK-801"
  • Ketamine (2-(2-chlorophenyl1)-(methylamino)-cyclohexanone hydrochloride)
    Ketamine is used as a veterinary and medical anaesthetic, and has dissociative/psychedelic effects at lower doses.
  • PCP (Phencyclidine)
  • Tiletamine (2-ethylamino-2-(2-thienyl)cyclohexanone)
• Barbiturates
  • Long-acting Barbiturates
    • Mephobarbital (5-ethyl-1-methyl-5-phenylbarbituric acid)
      "Mebaral", prescription anticonvulsant and sedative hypnotic
    • Phenobarbital (5-Ethyl-5-phenylbarbituric acid; Phenylethylbarbituric acid)
      Adonal; Luminal; Nunol; Solfoton, prescription anticonvulsant and sedative hypnotic
  • Ultra-short Acting Barbiturates
    • Methohexital (5-allyl-1-methyl-5-(1-methyl-2-pentenyl)barbituric acid)
      "Brevital"
    • Thiopental (5-ethyl-5-(1-methylbutyl)-2-thiobarbituric acid)
      Pentothal; "Truth serum"
  • Amobarbital (5-Ethyl-5-(3-methylbutyl)barbituric acid; 5-ethyl-5-isopentylbarbituric acid)
    Amytal; Tuinal; Amesec, prescription anticonvulsant and sedative hypnotic
  • Aprobarbital (5-Allyl-5-isopropylbarbituric acid; allyisopropyl-barbituric acid; allylisopropyl-malonylurea; 5-Ally-5-isopropyl barbituric acid)
    Alurate
  • Butabarbital
    Butisol, prescription sedative hypnotic
  • Pentobarbital (5-ethyl-5-(1-methylbutyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione; 5-Ethyl-5-(1-methylbutyl)barbituric acid)
    Nembutal, prescription sedative hypnotic
  • Secobarbital (5-Allyl-5-(1-methylbutyl)barbituric acid)
    Seconal, prescription sedative hypnotic
  • Talbutal (allyl-sec-butyl-barbituric acid; 5-Allyl-5-sec-butylbarbituric acid)
  • Thiamylal (5-Allyl-5-(1-methylbutyl)-2-thiobarbituric acid)
    Citosol
• Benzamide Derivatives (Includes Moclobemide, a MAOI commonly used in pharmahuasca)
  • Moclobemide (4-Chloro-N(2-morpholinoethyl)benzamide)
    Manerix, reversible MAOI used as an antidepressant in many countries outside the US.
• Benzodiazepines
  • Intermediate-acting Benzodiazepines
    • Clonazepam (5-(2-chlorophenyl)-1,3-dihydro-7-nitro2H-1,4-benzodiazepin-2-one)
      "Klonopin"
    • Lorazepam (7-chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one)
      "Ativan"
    • Quazepam (7-chloro-5-(o-fluorophenyl)-1,3-dihydro-1-(2,2,2-trifluoroethyl)-2H-1,4-benzodiazepin-2-thione)
      "Dormalin", "Doral"
  • Long-acting Benzodiazepines
    • Chlordiazepoxide (7-chloro-2-(methylamino)-5-phenyl-3H-1,4-benzodiazepin-4-oxide)
      "Librium"
    • Clorazepate
      "Tranxene"
    • Diazepam (7-chloro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one)
      "Valium"
    • Flurazepam
      "Dalmane"
    • Halazepam
      "Paxipam"
    • Prazepam (7-chloro-1-(cyclopropylmethyl)-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one)
      "Centrax"
  • Short-acting Benzodiazepines
    • Alprazolam (8-Chloro-1-methyl-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine)
      "Xanax"
    • Midazolam
      "Versed"
    • Oxazepam
      "Serax"
    • Temazepam
      "Restoril"
    • Triazolam
      "Halcion"
  • Flunitrazepam (5-(o-fluorophenyl)-1,3-dihydro-1-methyl-7-nitro-2H-1,4-benzodiazepin-2-one)
    Commonly called "Rohypnol"
  • Nitrazepam
  • Nordiazepam
• Bicyclic Terpenes (Includes Thujone, a chemical constituent of Absinthe)
  • Thujone
• Butyrophenones
  • Azaperone
    Stresnil, tranquilizer used in addition to ketamine or other anesthetics in veterinary medicine
  • Benperidol (1-(1-(3-(para-Fluorobenzoyl)propyl)-4-piperidyl)-2-benzimidazolinone hydrochloride monohydrate)
    Anquil, antipsychotic used to treat deviant, antisocial sexual behavior
  • Droperidol
    Inapsine, antipsychotic used as an adjunct to anethesia and antiemetic
  • Haloperidol (4-[4-(p-chlorophenyl)-4-hydroxypiperidino]-4'-fluorobutyrophenone)
    AKA: gamma-(4-(para-Chlorophenyl)-4-hydroxypiperidino)-para'-fluorobutyrophenone; "Serenace"
  • Melperone
    Antipsychotic
  • Spiperone (8-[3-(p-fluorobenzoyl)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one)
  • Trifluperidol
• Cannabinoids
  • 11-HO-THC (11-hydroxy-tetrahydrocannabinol)
    Primary active THC metabolite
  • 2-AG (sn-2 arachidonylglycerol)
  • Anandamide (Arachidonylethanolamide)
    The brain's endogenous cannabinoid.
  • Cannabidiol (2-[3-Methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-5-pentyl-1,3-benzenediol)
  • Cannabinol (3-n-Amyl-6,6,9-trimethyl-6-dibenzopyran-1-ol)
  • CP 55,940
    Partial agonist for both CB1 and CB2 receptors
  • Delta-6-THC
  • Dexanabinol
    A synthetic optic isomer of THC with neuroprotective qualities
  • HHC (9-nor-9B-hydroxy-hexahydrocannabinol)
  • HU-210
    extremely potent CB2 receptor agonist
  • Nabilone ((+-)-trans-3-(1,1-Dimethylheptyl)-6,6a,7,8,10,10a-hexahydro-1-hydroxy-6,6-dimethyl-9H-dibenzo[b,d]pyran-9-one)
    "Cesamet"; Prescribed to treat nausea
  • Propyl-THC
  • SR141716A
    Selective antagonist for CB1 cannabinoid receptors.
  • Synhexyl
    Synthetic cannabinoid
  • THC (Tetrahydrocannabinol; delta-9-tetrahydrocannabinol; delta-1-tetrahydrocannabinol)
    Primary chemical responsible for the psychoactive effects of cannabis.
• Carbamates
  • Carisoprodol (N-isopropyl 2-methyl-2-propyl-1,3-propanediol dicarbamate; isopropylcarbamic acid)
    Prescription relaxant marketed as "Soma"
  • Meprobamate (2-Methyl-2-propyl-1,3-propanediol dicarbamate)
    Antianxiety agent; Metabolite of carisoprodol
• Cocaine-related
  • Cocaine (Methylbenzoylecgonine)
  • Lidocaine (2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide)
  • Novocaine (Procaine hydrochloride; 4-aminobenzoic acid 2-(diethylamino)-ethyl ester hydrochloride)
• Elements and simple compounds
  • Lithium
    Often prescribed as Lithium carbonate, a mood stabilizer.
  • Nitrous oxide ("Laughing Gas")
    When inhaled, this gas acts as a dissociative anaesthetic. In addition to its ludible uses, it is a dental anaesthetic and is used industrially.
  • Xenon
    A noble gas; element #54 on the periodic table
• Ethanolamines
  • N-acylethanolamines ("NAEs")
    • N-linoleylethanolamine
    • N-oleyl-ethanolamine
  • Clenbuterol (4-amino-a-[(tert-butylamino)methyl]-3,5-dichlorobenzyl alcohol hydrochloride)
  • Dimenhydrinate (diphenhydramine 8-chlorotheophyllinate; 8-chlorotheophylline compound with 2-(diphenylmethoxy)-N,N-dimethylamine (1:1))
    "Dramamine™"; the 8-chlorotheophyllinate salt of diphenhydramine
  • Diphenhydramine (N,N-Dimethyl-4,4-diphenyl-3-oxabutylamine)
    Hydrochloride salt is marketed as "Benadryl™"
• GHB-related (Chemicals which are structurally similar to GHB and GBL)
  • 1,4-butanediol (GHB-alcohol; 1,4-butylene glycol; tetramethylene glycol; g-hydroxybutanol)
    Used industrially; Indirectly metabolized into GHB
  • 4-methyl-GHB (4-Hydroxyvalerate)
    Sodium 4-Hydroxyvalerate
  • Butyrate (n-butyric acid)
    Structural basis for a wide class of molecules
  • GABA (g-aminobutyric acid)
    Metabolite of ghb and neurotransmitter.
  • GBL (g-butyrolactone)
    Chemical and metabolic precursor to GHB
  • GHB (g-hydroxybutyrate)
    Sedative closely related in structure to GABA. Now a schedule I substance in the USA.
  • GHB-aldehyde (g-hydroxybutyraldehyde)
    metabolic precursor to ghb
• Glutamate-related
  • Glutamate (L-Glutamate; (S)-(+)-Glutamic Acid; Glutaminic acid; 2-Aminoglutaric acid)
    An amino acid found in all protein-containing foods. Produced by the human body; vital for metabolism and brain function.
  • MSG (DL-monosodium glutamate; sodium glutamate)
    Sodium salt of glutamate
  • Piracetam
    "Nootropyl"
• Indoles
  • Beta-carbolines (Class of indole alkaloids found in P. harmala and B. caapi)
    • 6-MeO-THH (6-methoxy-1-methyl-1,2,3,4-tetrahydro-b-carboline)
      Aldosterone-stimulating hormone. Tihkal #44.
    • Harmaline (3,4-dihydro-7-methoxy-1-methyl-b-carboline)
      Tihkal #13; Primary agent of P. harmala
    • Harmine (7-methoxy-1-methyl-b-carboline)
      Tihkal #14; primary active agent in B. caapi
    • Tetrahydroharmine (7-methoxy-1-methyl-1,2,3,4-tetrahydro-b-carboline)
      Is a serotonin reuptake inhibitor. Tihkal #54.
  • Corynantheine-related (Indole alkaloids from Yohimbe, Kratom, and others)
    • Corynantheidine
    • Corynantheine
    • Dihydrocorynantheine
    • Mitragynine (9-methoxy-corynantheidine)
      Primary active principle of Kratom
    • Paynanthine
    • Speciogynine
    • Yohimbine
  • Ergolines (Includes LSD and LSA)
    • Agroclavine
    • AL-LAD (N-(6)-allylnorlysergic acid, N,N-diethylamide)
      Tihkal #1.
    • ALD-52 (N-acetyl-LSD)
    • Elymoclavine
    • Ergonovine (9,10-Didehydro-N-(2-hydroxy-1-methylethyl)-6-methylergoline-8-carboxamide; Ergonovine)
    • Ergotamine (12-Hydroxy-2-methyl-5-(phenylmethyl)ergotaman-3,6,18-trione)
      Ergot alkaloid that is a precursor to LSD and related substances.
    • ETH-LAD (N-(6)-ethylnorlysergic acid, N,N-diethylamide)
      Tihkal #12.
    • Isoergine (D-isolysergic acid amide)
    • LSA (D-lysergic acid amide)
      Ergine
    • LSD (D-lysergic acid diethylamide)
      One of the most potent psychoactive drugs known, LSD is the prototypical psychedelic. Tihkal #26
    • Lysergene
    • Lysergic Acid
    • Lysergic acid hydroxyethylamide
    • Lysergine
    • Lysergol (9,10-Didehydro-8-hydroxymethyl-6-methyl-ergoline)
    • Methylergonovine (9,10-didehydro-N-[1(hydroxymethyl)propyl]-D-lysergamide)
    • Methysergide (1-methyl-D-lysergic acid butanolamide)
    • Penniclavine
    • PRO-LAD (6-propyl-nor-LSD)
      Tihkal #51.
    • Triseclavine
  • Iboganes (Class of indole alkaloids including those derived from the West African shrub, Tabernanthe iboga.)
    • Ibogaine (12-methoxyibogamine)
      Tihkal #25. This indole alkaloid with a distinctive (and synthetically difficult) seven-membered ring is under investigation as a cure for addiction.
    • Voacangine (carbomethoxy-ibogaine)
  • Tryptamines (Prototypical indole family including serotonin and such psychedelic drugs as DMT and psilocybin.)
    • 2,a-DMT (2,a-dimethyltryptamine)
      Tihkal #7.
    • 2-Me-DET (N,N-diethyl-2-methyl-tryptamine)
      Tihkal #33; noted for auditory and tactile distortion
    • 2-Me-DMT (2-N,N-trimethyltryptamine)
      Tihkal #34. Sensory stimulant, notably tactile.
    • 4,5-MDO-DIPT (N,N-diisopropyl-4,5-methylenedioxy-tryptamine)
      Tihkal #28.
    • 4,5-MDO-DMT (4,5-methylenedioxy-N,N-dimethyltryptamine)
      Tihkal #30.
    • 4-AcO-DIPT (4-acetoxy-N,N-diisopropyltryptamine)
      This ester of 4-OH-DIPT appeared on the gray market in late 1999.
    • 4-HO-DBT (4-hydroxy-N,N-dibutyltryptamine)
      Tihkal #15.
    • 4-HO-DET (4-hydroxy-N,N-diethyltryptamine)
      Tihkal #16.
    • 4-HO-DIPT (4-hydroxy-N,N-diisopropyltryptamine)
      Tihkal #17.
    • 4-HO-DPT (4-hydroxy-N,N-dipropyltryptamine)
      Tihkal #20.
    • 4-HO-MET (4-hydroxy-N-methyl-N-ethyltryptamine)
      Tihkal #21.
    • 4-HO-MIPT (4-hydroxy-N-methyl-N-isopropyltryptamine)
      Tihkal #22.
    • 4-HO-MPT (4-hydroxy-N-methyl-N-propyltryptamine)
      Tihkal #23.
    • 4-HO-pyr-T (4-hydroxy-N,N-tetramethylenetryptamine)
      Tihkal #24.
    • 4-MeO-MIPT (4-methoxy-N-methyl-N-isopropyltryptamine)
      Tihkal #39.
    • 4-PO-DET (4-phosphoryloxy-N,N-diethyltryptamine)
    • 5,6-MDO-DIPT (5,6-methylenedioxy-N,N-diisopropyltryptamine)
      Tihkal #29.
    • 5,6-MDO-DMT (5,6-methylenedioxy-N,N-dimethyltryptamine)
      Tihkal #31.
    • 5,6-MDO-MIPT (5,6-methylenedioxy-N-methyl-N-isopropyltryptamine)
      Tihkal #32.
    • 5,6-MeO-MIPT (5,6-dimethoxy-N-methyl-N-isopropyltryptamine)
      Tihkal #41.
    • 5-MeO-AMT (5-methoxy-a-methyltryptamine; a,O-DMS)
      Tihkal #5.
    • 5-MeO-DET (5-methoxy-N,N-diethyltryptamine)
      Tihkal #36.
    • 5-MeO-DIPT (5-methoxy-N,N-diisopropyltryptamine)
      Tihkal #37.
    • 5-MeO-DMT (5-methoxy-N,N-dimethyltryptamine)
      Tihkal #38.
    • 5-MeO-MIPT (5-methoxy-N-methyl-N-isopropyltryptamine)
      Tihkal #40.
    • 5-MeO-NMT (5-methoxy-N-methyltryptamine)
      Tihkal #42.
    • 5-MeO-pyr-T (5-methxoy-N,N-tetramethylenetryptamine)
      Tihkal #43.
    • 5-MeO-TMT (5-methoxy-2,N,N-trimethyltryptamine)
      Tihkal #45.
    • 5-MeS-DMT (5-methylthio-N,N-dimethyltryptamine)
      Tihkal #46.
    • AET (a-ethyl-tryptamine)
      Tihkal #11
    • a,N,O-TMS (5-methoxy-a,N-dimethyltryptamine)
      Tihkal #55.
    • a,N-DMT (a,N-dimethyltryptamine)
      Tihkal #8.
    • AMDIPT (a-methyl-N,N-diisopropyltryptamine)
      A rare and novel substance, probably placebo
    • AMT (a-methyltryptamine)
      Tihkal #48. Also known as IT-290.
    • Baeocystine (4-PO-MT; 4-phosphoryloxy-N-methyltryptamine)
    • Bufotenine (5-HO-DMT; 5-hydroxy-N,N-dimethyltryptamine)
      Tihkal #19
    • DBT (N,N-dibutyltryptamine)
      Tihkal #2.
    • DET (N,N-diethyltryptamine)
      Tihkal #3.
    • DIPT (N,N-diisopropyltryptamine)
      Tihkal #4; Noted for its unique auditory effects
    • DMT (N,N-dimethyltryptamine)
      Tihkal #6.
    • DPT (N,N-dipropyltryptamine)
      Tihkal #9.
    • EIPT (N-ethyl-N-isopropyltryptamine)
      Tihkal #10.
    • MBT (N-butyl-N-methyl-tryptamine)
      Tihkal #27.
    • Melatonin (N-acetyl-5-methoxytryptamine)
      Tihkal #35.
    • MIPT (N-methyl-N-isopropyltryptamine)
      Tihkal #47.
    • NET (N-ethyltryptamine)
      Tihkal #49.
    • NIPT (N-isopropyltryptamine)
    • NMT (N-methyltryptamine)
      Tihkal #50.
    • Norbaeocystine (4-phosphoryloxytryptamine)
    • Psilocin (4-HO-DMT; 4-hydroxy-N,N-dimethyltryptamine)
      Tihkal #18
    • Psilocybin (4-PO-DMT; 4-phosphoryloxy-N,N-dimethyltryptamine)
    • pyr-T (N,N-tetramethylenetryptamine)
      Tihkal #52.
    • Serotonin (5-HT; 5-hydroxytryptamine)
      An important neuromodulatory neurotransmitter whose receptors are the site of action of most psychedelic drugs
    • Tryptamine (3-(2-Aminoethyl)indole; 1H-Indole-3-ethanamine)
      Structural basis of a large class of psychedelic drugs, as well as the neurotransmitter serotonin, although not itself psychoactive. Tihkal #53.
  • 5-HTP (5-hydroxytryptophan)
    Metabolic precursor to Serotonin
  • Indole (2,3-benzopyrrole)
    A commonly used precursor in tryptamine chemistry
  • Strychnine
  • Tryptophan (3-indol-3-ylalanine; L-tryptophan)
    Amino acid that is the biosynthetic precursor for tryptamines in vivo.
• Kavalactones
  • DHM (Dihydromethysticin)
    Also known as pseudomethysticin
  • Dihydrokawain
    Also known as marindinin
  • Kawain (5,6-dihydro-4-methoxy-6-(2-phenylethenyl)-2H-pyran-2-one)
    Also known as kavain or gonosan
  • Methysticin
  • Yangonin
• Opioids
  • Opioid Agonists
    • Alfentanil
    • Codeine
      One of opium's active constituents
    • Fentanyl
      "Sublimaze"
    • Heroin (diacetylmorphine)
    • Hydrocodone (dihydrocodeinone)
      AKA Vicodin
    • Hydromorphone
      "Dilaudid"
    • Levorphanol
    • Meperidine
      "Demerol"
    • Methadone (6-Dimethylamino-4,4-diphenyl-3-heptanone; 1,1-Diphenyl-1-(2-dimethylaminopropyl)-2-butanone; 4,4-Diphenyl-6-dimethylamino-3-heptanone)
      Commonly used replacement in heroin addiction treatment
    • Morphine
      One of opium's active constituents and raw material from which heroin is obtained
    • Oxycodone (dihydrohydroxycodeinone)
      AKA percodan, percocet, oxycontin (sustained release)
    • Oxymorphone
      "Numorphan"
    • Propoxyphene
      AKA "Darvocet", "Darvon".
    • Sufentanil
  • Opioid Antagonists
    • Naloxone
    • Naltrexone
  • Opioid Partial Agonists
    • Buprenorphine
      "Buprenex"
    • Butorphanol
      "Stadol"
    • Dezocine
      "Dalgan"
    • Nalbuphine
      "Nubain"
    • Pentazocine
      "Talwin"
  • Dihydrocodeine
  • DXM (dextromethorphan)
    Cough-suppressing agent found in many over-the-counter cough and cold remedies; Dissociative at higher doses
  • DXO (dextrorphan)
    A metabolite of DXM, converted by the body through O-demethylation
  • Levomethorphan
    Opiate stereoisomer of DXM
  • Nalorphine
  • Papaverine
    One of opium's active constituents
• Oxazoles (Includes chemical constituents of Amanita muscaria)
  • 4-methylaminorex (dl-cis-2-amino-4-methyl-5-phenyl-2-oxazoline)
  • Ibotenic acid (a-amino-2,3-dihydro-3-oxo-5-isoxazoleacetic acid)
  • Muscimol
  • Pemoline (2-Amino-5-phenyl-4-(5H)oxazolone)
    "Cylert"
  • Tricholomic acid (L-erythro-a-amino-3-oxo-5-isoxazolidine acetic acid; dihydro-ibotenic acid)
• Phenethylamines (Includes mescaline, MDMA, amphetamines, and precursors.)
  • Amphetamines, Analogs, and Precursors (Amphetamine and its stimulant analogs, as well as synthetic precursors.)
    • ALEPH-2 (4-ethylthio-2,5-dimethoxyamphetamine)
    • Amphetamine (a-methylphenethylamine)
    • Benzphetamine (Benzfetamine; N-Benzyl-N,a-dimethylbenzeneethanamine)
      Didrex
    • b-Asarone (cis-1-propenyl-2,4,5-trimethoxybenzol)
    • Cathinone ((-)-a-Aminopropiophenone)
    • Elemicin (5-allyl-1,2,3-trimethoxybenzene)
      Present in nutmeg
    • Ephedrine
    • Eugenol
    • Fenfluramine
      "Pondimin"
    • Isosafrole
    • MDP2P (3,4-methylenedioxy-phenyl-2-propanone)
      Precursor to MDMA, MDA, and related chemicals.
    • Methamphetamine (N-methylamphetamine)
    • Methcathinone
    • Methylamine (Monomethylamine)
      Important reagent in the synthesis of MDMA and Methamphetamine.
    • Methylphenidate
      alpha-Phenyl-2-piperidineacetic acid methyl ester; "Ritalin[tm]"
    • Myristicin (3-methoxy,4,5-methylendioxy-allylbenzene)
      Non-amine precursor of 3-methoxy-4,5-methylenedioxyamphetamine.
    • P2P (phenyl-2-propanone)
      Common amphetamine precursor.
    • Phenylalanine
      Amino acid and biosynthetic precursor
    • Phenylpropanolamine (2-amino-1-phenyl-1-propanol)
    • PMA (Paramethoxyamphetamine, 4-MA, 4-methoxyamphetamine)
      A strong stimulant, toxic, sometimes found in or represented as ecstasy
    • Pseudoephedrine
    • Safrole (3,4-methylene-dioxyallylbenzene)
      Non-amine precursor to 3,4-methylenedioxyamphetamine
  • Psychedelic Amphetamines (Includes MDMA, DOB, DOM, TMA-2 and many others described in PIHKAL)
    • 2,4-DMA (2,4-dimethoxyamphetamine)
    • 2,5-DMA (2,5-dimethoxyamphetamine)
    • 2-Br-4,5-MDA (2-bromo-4,5-methylenedioxyamphetamine)
    • 2-TOET (4-ethyl-5-methoxy-2-methylthioamphetamine)
    • 2-TOM (5-methoxy-4-methyl-2-methylthioamphetamine)
    • 2T-MMDA-3a (2-methylthio-3,4-methylenedioxyamphetamine)
    • 3,4-DMA (3,4-dimethoxyamphetamine)
    • 3C-BZ (4-benzyloxy-3,5-dimethoxyamphetamine)
    • 3C-E (4-ethoxy-3,5-dimethoxyamphetamine)
    • 4-Br-3,5-DMA (4-bromo-3,5-dimethoxyamphetamine)
    • 4T-MMDA-2 (4,5-thiomethyleneoxy-2-methoxyamphetamine)
    • 5-TOET (4-ethyl-2-methoxy-5-methylthioamphetamine)
    • 5-TOM (2-methoxy-4-methyl-5-methylthioamphetamine)
    • ALEPH (4-methylthio-2,5-dimethoxyamphetamine)
    • ALEPH-4 (4-isopropylthio-2,5-dimethoxyamphetamine)
    • ALEPH-6 (4-phenylthio-2,5-dimethoxyamphetamine)
    • ALEPH-7 (4-propylthio-2,5-dimethoxyamphetamine)
    • BEATRICE (2,5-dimethoxy-4,N-dimethylamphetamine)
    • BIS-TOM (2,5-bismethylthio-4-methylamphetamine)
    • DMMDA (2,5-dimethoxy-3,4-methylenedioxyamphetamine)
    • DMMDA-2 (2,3-dimethoxy-4,5-methylenedioxyamphetamine)
    • DMPEA (3,4-dimethoxyphenethylamine)
    • DOAM (4-amyl-2,5-dimethoxyamphetamine)
    • DOB (2,5-dimethoxy-4-bromo-amphetamine)
      Active at doses of only a few mg, this psychedelic is the amphetamine analog of 2C-B
    • DOBU (4-butyl-2,5-dimethoxyamphetamine)
    • DOC (4-chloro-2,5-dimethoxyamphetamine)
    • DOEF (4-2-fluoroethyl-2,5-dimethoxyamphetamine)
    • DOET (4-ethyl-2,5-dimethoxyamphetamine)
    • DOI (2,5-dimethoxy-4-iodoamphetamine)
    • DOM (2,5-dimethoxy-4-methylamphetamine)
    • DON (4-nitro-2,5-dimethoxyamphetamine)
    • DOPR (4-propyl-2,5-dimethoxyamphetamine)
    • EEE (2,4,5-triethoxyamphetamine)
    • EEM (2,4-diethoxy-5-methoxyamphetamine)
    • EME (2,5-diethoxy-4-methoxyamphetamine)
    • EMM (2-ethoxy-4,5-dimethoxyamphetamine)
    • FLEA (N-hydroxy-N-methyl-3,4-methylenedioxyamphetamine)
    • G-3 (3,4-trimethylene-2,5-dimethoxyamphetamine)
    • G-4 (3,4-tetramethylene-2,5-dimethoxyamphetamine)
    • G-5 (3,4-norbornyl-2,5-dimethoxyamphetamine)
    • GANESHA (3,4-dimethyl-2,5-dimethoxyamphetamine)
    • IRIS (4-ethoxy-2-methoxy-4-methylamphetamine)
    • MADAM-6 (2,N-dimethyl-4,5-methylenedioxyamphetamine)
    • MDA (3,4-methylenedioxyamphetamine)
    • MDAL (N-allyl-3,4-methylenedioxyamphetamine)
    • MDBU (N-butyl-3,4-methylenedioxyamphetamine)
    • MDBZ (N-benzyl-3,4-methylenedioxyamphetamine)
    • MDCPM (N-cyclopropylmethyl-3,4-methylenedioxyamphetamine)
    • MDDM (N,N-dimethyl-3,4-methylenedioxyamphetamine)
    • MDE (3,4-methylenedioxy-N-ethylamphetamine)
    • MDHOET (N-2-hydroxyethyl-3,4-methylenedioxyamphetamine)
    • MDIP (N-isopropyl-3,4-methylenedioxyamphetamine)
    • MDMA (3,4-methylenedioxy-N-methylamphetamine)
      "Ecstasy"
    • MDMC (N-methyl-3,4-ethylenedioxyamphetamine)
    • MDMEO (N-methoxy-3,4-methylenedioxyamphetamine)
    • MDMEOET (N-2-methoxyethyl-3,4-methylenedioxyamphetamine)
    • MDMP (a,a,N-trimethyl-3,4-methylenedioxyamphetamine)
    • MDOH (N-hydroxy-3,4-methylenedioxyamphetamine)
    • MDPL (N-propargyl-3,4-methylenedioxyamphetamine)
    • MDPR (N-propyl-3,4-methylenedioxyamphetamine)
    • MEDA (3,4-ethylenedioxy-5-methoxyamphetamine)
    • MEE (2-methoxy-4,5-diethoxyamphetamine)
    • MEM (2,5-dimethoxy-4-ethoxyamphetamine)
    • META-DOB (5-bromo-2,4-dimethoxyamphetamine)
    • META-DOT (5-methylthio-2,4-dimethoxyamphetamine)
    • METHYL-DMA (N-2,5-dimethoxyamphetamine)
    • METHYL-DOB (4-bromo-2,5-dimethoxy-N-methylamphetamine)
    • METHYL-MA (N-4-methoxyamphetamine)
    • METHYL-MMDA-2 (N-methyl-2-methoxy-4,5-methylenedioxyamphetamine)
    • MMDA (3-methoxy-4,5-methylenedioxyamphetamine)
    • MMDA-2 (2-methoxy-4,5-methylenedioxyamphetamine)
    • MMDA-3a (2-methoxy-3,4-methylenedioxyamphetamine)
    • MMDA-3b (4-methoxy-2,3-methylenedioxyamphetamine)
    • MME (2,4-dimethoxy-5-ethoxyamphetamine)
    • MPM (2,5-dimethoxy-4-propoxyamphetamine)
    • MTA (4-methylthioamphetamine)
    • ORTHO-DOT (2-methylthio-4,5-dimethoxyamphetamine)
    • Psi-DOM (4-methyl-2,6-dimethoxyamphetamine)
    • TA (2,3,4,5-tetramethoxyamphetamine)
    • TMA (3,4,5-trimethoxyamphetamine)
    • TMA-2 (2,4,5-trimethoxyamphetamine)
    • TMA-3 (2,3,4-trimethoxyamphetamine)
    • TMA-4 (2,3,5-trimethoxyamphetamine)
    • TMA-5 (2,3,5-trimethoxyamphetamine)
    • TMA-6 (2,4,6-trimethoxyamphetamine)
    • TOMSO (2-methoxy-4-methyl-5-methylsulfinylamphetamine)
  • 2-TIM (2-methylthio-3,4-dimethoxyphenethylamine)
  • 2C-B (4-bromo-2,5-dimethoxyphenethylamine)
  • 2C-C (4-chloro-2,5-dimethoxyphenethylamine)
  • 2C-D (2,5-dimethoxy-4-methylphenethylamine)
  • 2C-E (4-ethyl-2,5-dimethoxyphenethylamine)
  • 2C-F (4-fluoro-2,5,dimethoxyphenethylamine)
  • 2C-G (3,4-dimethyl-2,5-dimethoxyphenethylamine)
  • 2C-G-3 (3,5-trimethylene-2,5-dimethoxyphenethylamine)
  • 2C-G-4 (3,4,tetramethylene-2,5-dimethoxyphenethylamine)
  • 2C-G-5 (3,4-norbornyl-2,5-dimethoxyphenethylamine)
  • 2C-G-N (1,4-dimethoxynaphthyl-2-ethylamine)
  • 2C-H (2,5-dimethoxyphenethylamine)
  • 2C-I (4-iodo-2,5-dimethoxyphenethylamine)
  • 2C-N (4-nitro-2,5-dimethoxyphenethylamine)
  • 2C-O-4 (4-isopropoxy-2,5-dimethoxyphenethylamine)
  • 2C-P (4-propyl-2,5-dimethoxyphenethylamine)
  • 2C-SE (4-methylseleno-2,5-dimethoxyphenethylamine)
  • 2C-T (4-methylthio-2,5-dimethoxyphenethylamine)
  • 2C-T-13 (4-2-methoxyethylthio-2,5-dimethoxyphenethylamine)
  • 2C-T-15 (4-cyclopropylthio-2,5-dimethoxyphenethylamine)
  • 2C-T-17 (4-sec-butylthio-2,5-dimethoxyphenethylamine)
  • 2C-T-2 (4-ethylthio-2,5-dimethxoyphenethylamine)
  • 2C-T-21 (4-2-fluoroethylthio-2,5-dimethoxyphenethylamine)
  • 2C-T-4 (4-isopropylthio-2,5-dimethoxyphenethylamine)
  • 2C-T-7 (4-propylthio-2,5-dimethoxyphenethylamine)
  • 2C-T-8 (4-cyclopropylmethylthio-2,5-dimethoxyphenethylamine)
  • 2C-T-9 (4-tert-butylthio-2,5-dimethoxyphenethylamine)
  • 3-T-TRIS (4,5-diethoxy-3-ethylthiophenethylamine)
  • 3-TASB (4-ethoxy-3-ethylthio-5-methoxyphenethylamine)
  • 3-TE (4-ethoxy-5-methoxy-3-methylthiophenethylamine)
  • 3-TIM (3-methylthio-2,2-dimethoxyphenethylamine)
  • 3-TM (3-methylthio-4,5-dimethoxyphenethylamine)
  • 3-TME (4,5-dimethoxy-3-ethylthiophenethylamine)
  • 3-TSB (3-ethoxy-5-ethylthio-5-methoxyphenethylamine)
  • 4-D (4-trideuteromethyl-3,5-dimethoxyphenethylamine)
  • 4-T-TRIS (3,5-diethoxy-4-ethylthiophenethylamine)
  • 4-TASB (3-ethoxy-4-ethylthio-5-methoxyphenethylamine)
  • 4-TE (3,5-dimethoxy-4-ethylthiophenethylamine)
  • 4-TIM (4-methylthio-2,3-dimethoxyphenethylamine)
  • 4-TM (4-methylthio-3,5-dimethoxyphenethylamine)
  • 4-TME (3-ethoxy-5-methoxy-4-methylthiophenethylamine)
  • 4-TSB (3,5-diethoxy-4-methylthiophenethylamine)
  • 5-TASB (3,4-diethoxy-5-methylthiophenethylamine)
  • 5-TME (3-ethoxy-4-methoxy-5-methylthiophenethylamine)
  • AEM (a-ethylmescaline)
  • AL (4-allyloxy-3,5-dimethoxyphenethylamine)
  • ARIADNE (2,5-dimethoxy-a-ethyl-4-methylphenethylamine)
  • ASB (3,4-dimethoxy-5-methoxyphenethylamine)
  • B (buscaline, 4-butoxy-3,5-dimethoxyphenethylamine)
  • b-D (b,b-dideutero-3,4,5-trimethoxy-phenethylamine)
  • BOB (4-bromo-2,5,b-hydroxy-4-methylphenethylamine)
  • BOD (2,5,b-trimethoxy-4-methylphenethylamine)
  • BOH (b-methoxy-3,4-methylenedioxyphenethylamine)
  • BOHD (2,5-dimethoxy-b-hydroxy-4-methylphenethylamine)
  • BOM (3,4,5,b-tetramethoxyphenethylamine)
  • CPM (4-cyclopropylmethoxy-3,5-dimethoxyphenethylamine)
  • DESOXY (4-methyl-3,5-dimethoxyphenethylamine)
  • DMCPA (2-2,5-dimethoxy-4-methylphenyl-cyclopropylamine)
  • DME (3,4-dimethoxy-b-hydroxyphenethylamine)
  • Dopamine (3,4-dihydroxyphenethylamine)
  • E (escaline, 4-ethoxy-3,5-dimethoxyphenethylamine)
  • ETHYL-J (N-a-diethyl-3,4-methylenedioxyphenethylamine)
  • ETHYL-K (N-ethyl-a-propyl-3,4-methylenedioxyphenethylamine)
  • F-2 (benzofuran-2-methyl-5-methoxy-6-2-aminopropane)
  • F-22 (benzofuran-2,2-dimethyl-5-methoxy-6-2-aminopropane)
  • G-N (1,4-dimethoxynaphthyl-2-isopropylamine)
  • HOT-17 (2,5-dimethoxy-N-hydroxy-4-secbutylthiophenethylamine)
  • HOT-2 (2,5-dimethoxy-N-hydroxy-4-ethylthiophenethylamine)
  • HOT-7 (2,5-dimethoxy-N-hydrox-4-n-propylthiophenethylamine)
  • IDNNA (2,5-dimethoxy-N,Ndimethyl-4-iodophenethylamine)
  • IM (isomescaline, 2,3,4-trimethoxyphenethylamine)
  • IP (isoproscaline, 3,5-dimethoxy-4-isopropoxyphenethylamine)
  • J (a-ethyl-3,4-methylenedioxyphenethylamine)
  • LOPHOPHINE (3-methoxy-4,5-methylenedioxyphenethylamine)
  • MAL (3,4-dimethoxy-4-methallyloxyphenethylamine)
  • MDPEA (3,4-methylenedioxyphenethylamine)
  • MDPH (a,a-dimethyl-3,4-methylenedioxyphenethylamine)
  • ME (metaescaline, 3,4-dimethoxy-5-ethoxyphenethylamine)
  • MEPEA (3-methoxy-4-ethoxyphenethylamine)
  • Mescaline (3,4,5-trimethoxyphenethylamine)
  • METHYL-J (N-methyl-a-ethyl-3,4-methylenedioxyphenethylamine)
  • METHYL-K (N-methyl-a-propyl-3,4-methylenedioxyphenethylamine)
  • MP (metaproscaline, 3,4-dimethoxy-5-propoxyphenethylamine)
  • PE (phenescaline, 3,5-dimethoxy-4-phenethyloxyphenethylamine)
  • PEA (phenethylamine)
  • Phenelzine
    Antidepressant MAOI
  • Phenethylamine (b-phenethylamine)
  • PROPYNYL (4-propynyloxy-3,5-dimethoxyphenethylamine)
  • Proscaline (3,5-dimethoxy-4-propoxyphenethylamine)
  • Psi-2C-T-4 (4-isopropylthio-2,6-dimethoxyphenethylamine)
  • SB (symbescaline, 3,5-diethoxy-4-methoxyphenethylamine)
  • TB (thiobuscaline, 4-thiobutoxy-3,5-dimethoxyphenethylamine)
  • TMPEA (2,4,5-trimethoxyphenethylamine)
  • TP (thioproscaline, 4-propylthio-3,5-dimethoxyphenethylamine)
  • TRIS (3,4,5-triethoxyphenethylamine)
• Piperazines
  • Piperazine-based antihistamines
    • Cyclizine
      "Marezine"; Motion-sickness drug similar in action to Dramamine
    • Meclizine
      Meclozine; Meclizine hydrocloride ("Dramamine II")
  • BZP (benzylpiperazine)
    Marketed in Europe as "A2"
  • CPP (1-(3-Chlorophenyl)piperazine)
  • MeOPP (1-(4-Methoxyphenyl)piperazine)
  • Sildenafil citrate (1-[[3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo [4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine citrate)
    "Viagra"
  • TFMPP (1-(3-triflouromethylphenyl)piperazine)
• Propiophenones
  • Bupropion
    "Wellbutrin", "Zyban"
• Pyrrolidines and Pyridines
  • Imidzopyridines
    • Zolpidem
      "Ambien", a non-benzodiazepine sedative-hypnotic.
  • Piperadines
    • Anabasine (Neonicotine; Pyridylpiperidine)
    • Paroxetine (Paxil; (-)-trans-4R-(4'-fluorophenyl)-3S-((3',4'-methylenedioxyphenoxy)methyl)piperidine)
    • Piperidine (Hexahydropyridine; azacyclohexane; cyclopentimine)
      Structural component of many psychoactive drugs, although a hazardous material itself.
  • Acetylcholine
  • Anatabine
  • Arecoline
    Present in Betel Nut
  • Cotinine ((S)-1-methyl-5-(3-pyridinyl)-2-Pyrrolidinone; 1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone)
  • Glutethimide (2-Ethyl-2-phenylglutarimide)
    "Doriden"
  • Methyprylon (3,3-Diethyl-5-methyl-2,4-piperidinedione; Dimerin)
  • MPTP (1,2,3,6-tetrahydro-1-methyl-4-phenylpyridine)
    This byproduct of a faulty designer opiate synthesis caused symptoms of Parkinsonism in some addicts.
  • Myosmine
  • Nicotine (1-methyl-2-(3-pyridyl)pyrolidine)
  • Nornicotine (3-(1-Pyrrolidin-2-yl)pyridine)
• Quinazolines
  • Methaqualone (3,4-dihydro-2-methyl-4-oxo-3-o-tolylquinazoline)
    Commonly called Quaalude
• Salvinorin-related
  • Salviarin
    Present in S. splendens
  • Salvinorin-A
    Most potent naturally-occuring entheogenic chemical yet discovered; Active constituent of Salvia divinorum
  • Salvinorin-B
    Non-psychoactive constituent of Salvia divinorum
  • Splendidin
    Present in S. splendens
• Thiazines
  • Phenothiazines
    • Chlorpromazine
      "Thorazine"
    • Fluphenazine
      "Prolixin"
    • Prochlorpromazine
      "Compazine"
    • Trifluoperazine
      "Stelazine"
  • Xylazine (2-(2,6-xylidino)-5,6-dihydro-4H-1,3-thiazine)
    Sedative/anesthetic/analgesic sometimes administered with ketamine to animals
• Tropanes (Extremely powerful and dangerous psychoactive anticholinergic drugs. Found in many species of Solanaceous plants such as Belladonna.)
  • Atropine
  • BZ (3-quinuclidinyl benzillate)
    Investigated by the US military as a chemical warfare agent.
  • Scopolamine
• Xanthines (Methylxanthines - Includes chemical constituents of chocolate and coffee)
  • 8-Chlorotheophylline (8-Chloro-1,3-dimethyl-2,6(1H,3H)-purinedione)
  • Caffeine (1,3,7-trimethylxanthine)
    The most popular psychoactive drug in the world. Use of this stimulant is encouraged in most workplaces, although it can be physically addictive.
  • Theobromine (3,7-dimethylxanthine)
    produced by cocoa beans; present in all chocolate products
  • Theophylline (3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione; 1,3-dimethylxanthine)
• Acetaminophen (4-Acetamidophenol; Tylenol; paracetamol; Acetaminofen)
  Common analgesic
• Adrenochrome (3-Hydroxy-1-methyl-5,6-indoline-dione)
  Produced in the body by oxidation of epinephrine (andrenalin).
• Anhalonine
  Present in peyote cacti
• BuSpirone (8-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4,5]decane-7,9-dione)
  Buspar, non-benzodiazepine anxiolytic tranquilizer
• Camphor (2-Camphanone; 1,7,7-Trimethylnorcamphor)
  white, crystalline solid ketone with a characteristic pungent odor and taste
• Capsicum (Oleoresin capsicum)
  Dark red viscous liquid
• Chlorpheniramine
  Over-the-counter antihistamine added to a variety of cold medicines
• Chrysin (5,7-Dihydroxyflavone)
• Cinnamaldehyde (3-Phenyl-2-propenal; Cinnamic aldehyde)
  Primary constituent of cinnamon oil
• Diethylpropion (2-(Diethylamino)propiophenone)
• Eucalyptol (1,8-Cineole; 1,8-epoxy-p-menthane)
• Femoxetine
• Fluvoxamine
• Hordenine
  Present in peyote cacti
• Methyl salicylate (2-carbomethoxyphenol; methyl o-hydroxybenzoate)
  Oil of wintergreen
• N-Acetylmescaline
  Present in peyote cacti
• N-Methylmescaline (Benzenethanamine,3,4,5-trimethoxy-N-methyl-)
  Present in peyote cacti
• Pellotine
  Present in peyote cacti
• Phenmetrazine (3-Methyl-2-phenylmorpholine; 2-phenyl-3 methyl-tetrahydro-1,4-oxazine)
  Preludin
• Phentermine (a,a-Dimethylphenethylamine;a,a-dimethylbenzeneethanamine; Phenyl-tertiary-butylamine; Ethanamine)
• Selegiline
  "Deprenyl", "Eldepryl", "Jumex"
• Thymol (6-Isopropyl-m-cresol; 3-Hydroxy-p-cymene)
• Tyramine (tyrosamine; 4-(2-Aminoethyl)phenol; 2-(p-Hydroxyphenyl)ethylamine; L-Tyramine; 4-Hydroxyphenylethylamine)
• Venlafaxine