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Author Topic: propionic/acetic anhydride esterification of loperamide  (Read 5517 times)

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Offline tryl

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propionic/acetic anhydride esterification of loperamide
« on: August 06, 2010, 06:16:45 pm »
the odyssey continues.

again, just spreading the word, all merit goes to beebo and jon from wetdreams.

apparently lope citrate is both water soluble, crosses readily the BBB, is dirt cheap OTC, perfectly legal, at least 10x the potency of morphine, and lasts ~2 days.

a junkie's wet dream.

many people have so far experimented with it, and everybody says the same.
its too fkn potent to be placebo.

so.

get yerself acetic anhydride from whichever vendor readily supplying in small quantities , or buy/make yourself propionic anhydride (check sciencemadness).

now, lope you can either buy pure & in bulk from chinese wholesalers, or get some of those $5 for 700x2mg offers from stores
grind pills, clean with hot naptha, extract thrice with MeOH, evap.

and there's your lope.

275mg loperamide + 3cc propionic/acetic anhydride + sodium acetate (catalyst) shoved together in a small sealed container and placed in 100ml boiling water.

cook, open, evap, further purify if necessary (probably a good idea to do it at least once) & dry.

that's it.

you can now readily dissolve the shit in water and slam it, with shocking results.

about to confirm this myself.

(some of these folks have been doing this for 2+ years!  :-o )



 
« Last Edit: August 10, 2010, 02:53:29 pm by ST1R »
his pants will be crusted with semen from constantly jerking off whenever he can't find a rape victim.

in the words of archimedes - give me a lever and a place to put it... or i shall kill a hostage every hour.

Offline foreward

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Re: propionic/acetic anhydride esterification of loperamide
« Reply #1 on: August 06, 2010, 06:22:14 pm »
nice post, I've been following this development from the starts.

Though the sources, ya know...
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Offline jc

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Re: propionic/acetic anhydride esterification of loperamide
« Reply #2 on: August 06, 2010, 06:28:16 pm »
Nice find if it actually works. I'll be trying it this week myself.  thanks ;D
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Offline tryl

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Re: propionic/acetic anhydride esterification of loperamide
« Reply #3 on: August 06, 2010, 07:19:55 pm »
Nice find if it actually works. I'll be trying it this week myself.  thanks ;D

do share the results.


his pants will be crusted with semen from constantly jerking off whenever he can't find a rape victim.

in the words of archimedes - give me a lever and a place to put it... or i shall kill a hostage every hour.

Offline jc

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Re: propionic/acetic anhydride esterification of loperamide
« Reply #4 on: August 06, 2010, 07:23:33 pm »
of course i will, unless it kills me which would become somewhat self-evident anyways
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Offline jc

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Re: propionic/acetic anhydride esterification of loperamide
« Reply #5 on: August 08, 2010, 07:29:34 pm »
nice post, I've been following this development from the starts.

Though the sources, ya know...

lol bbb isn't (just) a source, it means blood brain barrier;)
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Offline foreward

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Re: propionic/acetic anhydride esterification of loperamide
« Reply #6 on: August 08, 2010, 08:00:17 pm »
uhm. you're joking, right? my sense-of-humor is running at a deficit.
I've seen it happen in other people's lives, and now it's happening in mine. -The Smiths

Offline Dr. Toxicophilous

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Re: propionic/acetic anhydride esterification of loperamide
« Reply #7 on: August 08, 2010, 09:00:26 pm »
It's no joke. You can reference the "Loperamide -> 4 Day Smack" thread if you like.
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Offline foreward

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Re: propionic/acetic anhydride esterification of loperamide
« Reply #8 on: August 09, 2010, 09:32:22 am »
i meant the bbb thing. like I said, I've been following this for a while.

Quote
get yerself acetic anhydride from whichever vendor readily supplying in small quantities (PM me if you dont know any), or buy/make yourself propionic anhydride (check sciencemadness).

now, lope you can either buy pure & in bulk from chinese wholesalers, or get some of those $5 for 700x2mg offers from xxx or xxx.


I thought that discussing any sources as against "the rules" regardless what it is or it's legal status?
« Last Edit: August 09, 2010, 09:33:33 am by foreward »
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Offline jc

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Re: propionic/acetic anhydride esterification of loperamide
« Reply #9 on: August 09, 2010, 08:21:30 pm »
 I don't think saying which country has something really counts as a source; it has been my understanding that specific sources are what was mean by that regulation.
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Offline foreward

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Re: propionic/acetic anhydride esterification of loperamide
« Reply #10 on: August 09, 2010, 08:30:28 pm »
holy fucking shit man! read the post! the sources are right fucking there! I edited them out of my reply. It's not just what country, trylo included a specific department store chain and a specific internet auction website. he also said to PM him for details on where to get acetic acid, which I thought was also against the rules.

You people MUST be fucking with me or something.... trying to make me look like a lycaeum company man bureaucrat err something... i mean, it's RIGHT THERE!!!!
« Last Edit: August 09, 2010, 08:33:10 pm by foreward »
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Offline jc

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Re: propionic/acetic anhydride esterification of loperamide
« Reply #11 on: August 09, 2010, 08:43:52 pm »
Is someone fucking with me?  I honestly still can't see a source in this thread.  Unless you mean where to find out how to make the propionic acid; that site isn't a vendor site, it is actually a pretty good science news site, but they don't sell anything afaik tho?  I know it is probably right in front of me and I am just to stupid to see it.
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Offline foreward

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Re: propionic/acetic anhydride esterification of loperamide
« Reply #12 on: August 09, 2010, 10:05:55 pm »
refer to reply #8 and look at those lines in the original post... if you still can't see it i'm just going to assume I'm tripping...
I've seen it happen in other people's lives, and now it's happening in mine. -The Smiths

Offline Dr. Toxicophilous

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Re: propionic/acetic anhydride esterification of loperamide
« Reply #13 on: August 10, 2010, 12:57:53 am »
sciencemadness is not a source. It's just another chemistry forum, albeit one of the more advanced ones in existence, across all chemistry related disciplines. Org, inorg, electrochem etc etc

Acetic acid is just concentrated vinegar. Evap or distill off the water to get near glacial acetic acid. Glacial itself is readily available and cheap from photography supply and other outlets.

He's given people the references of where to look, but no sources.

The post breaks no rules.
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Offline jc

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Re: propionic/acetic anhydride esterification of loperamide
« Reply #14 on: August 10, 2010, 05:17:59 am »
 
refer to reply #8 and look at those lines in the original post... if you still can't see it i'm just going to assume I'm tripping...

No, you are totally right; it is I who must of been tripping.
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Offline foreward

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Re: propionic/acetic anhydride esterification of loperamide
« Reply #15 on: August 10, 2010, 12:11:37 pm »
Thanks luc. I know that we don't often actually read posts, but seriously, this is ridiculous. It says right there, specifically where to obtain Loperamide! If we had the STORE which trylo conveniently listed locally I could go there and buy some... Oh wait... He also told me where to obtain it online. WTF! If that isn't sourcing, I dunno what is!

Jesus, where the hell are the moderators?? I've sent a letter to tryp but he didn't reply.
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Offline tryl

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Re: propionic/acetic anhydride esterification of loperamide
« Reply #16 on: August 10, 2010, 01:28:56 pm »
this now is absolutely, totally unnecessary waste of space.
why are you hijacking the thread with something that.. doesn't really even matter?
you can find hen's teeth online for fuck sake.
everybody knows that.
check out wetdreams, they have the same rules about sources, and they make mention of both stores in the very same context.
why are you so actively concerned about something so insignificant?
« Last Edit: August 10, 2010, 02:52:32 pm by ST1R »
his pants will be crusted with semen from constantly jerking off whenever he can't find a rape victim.

in the words of archimedes - give me a lever and a place to put it... or i shall kill a hostage every hour.

Offline foreward

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Re: propionic/acetic anhydride esterification of loperamide
« Reply #17 on: August 10, 2010, 02:10:16 pm »
OH! OK! so those two sources are excluded from source listing rules.

Dood, you know why we have these rules, both for legal and for harm reduction purposes. Anyone who is qualified to do any type of synthesis, even simple ones like this, should have the know how to get basic ingredients. Furthermore there is a possibility that the lyc could be wrapped up in some kind of BS federal conspiracy lawsuit if it gets out of hand.

I am really sorry though that this thread was hijacked, I shouldn't have gotten into it so much. I just should have mentioned it the way I did and notified the mods. So yeah, I am really sorry about that, but I still don't think that those two sources are excluded from source listing just because they sell other stuff, too. You have listed them in the context of a synthesis, not where to buy hen's teeth or a 10 gallon jar of pickles.

But anyway, please continue on topic. I am sorry for my interruption. It just got out of hand, ya know?
« Last Edit: August 10, 2010, 02:25:09 pm by foreward »
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Offline ST1R

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Re: propionic/acetic anhydride esterification of loperamide
« Reply #18 on: August 10, 2010, 02:55:39 pm »
forward is right. trilos posts edited. NO sourcing regardless of legality.

Continue discussion.
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Offline tryl

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Re: propionic/acetic anhydride esterification of loperamide
« Reply #19 on: August 10, 2010, 03:56:32 pm »
whatever.

dont give much of a fuck.

try to make a post/convo about something interesting, whole thing goes down the drain for something as stoopid as an argument about source-mentioning, when, as Mis noted, i just gave hints about where to look.

big fckn deal. hope you didn't loose any sleep over it.

im sorry too, for not hiding my irritation about this, but i'll abstain from posting such things/finds here from now on and participate where they do generate interest and do not degenerate into arguments about "forum rules".


his pants will be crusted with semen from constantly jerking off whenever he can't find a rape victim.

in the words of archimedes - give me a lever and a place to put it... or i shall kill a hostage every hour.

Offline Dr. Toxicophilous

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Re: propionic/acetic anhydride esterification of loperamide
« Reply #20 on: August 10, 2010, 06:28:06 pm »
What. THe. Fuck.... WHAT SOURCES???? BBB? Sciencemadness????

BBB is blood brain barrier and not the "STORE" I think you're talking about.

The fuck gives people???
Perplext no more with Human or Divine,
To-morrow's tangle to the winds resign,
And lose your fingers in the tresses of
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Offline ST1R

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Re: propionic/acetic anhydride esterification of loperamide
« Reply #21 on: August 10, 2010, 06:44:03 pm »
Trilo named specific sites and stores thats a no-no.
"Chemistry is pornography in disguise, you just have to know which functional group to look at."
A. Shulgin
"If we knew what we were doing, it wouldn't be called research."
A. Einstein
"Have you never seen anybody that knows not much? Does your grandma make lsd for you in christmas?"
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Offline jc

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Re: propionic/acetic anhydride esterification of loperamide
« Reply #22 on: September 05, 2010, 11:45:01 am »
This really did seem to work.  Dosed yesterday and I think I might still be a little high.  I was around maybe 10-15mg.  I felt like i was moving sluggishly and jerkily, but was probably largely in my head.  There were also random waves of warmth like i was coming down with a fever, but they never lasted and felt good.  I don't know that I actually got any euphoria.
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Offline tryl

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Re: propionic/acetic anhydride esterification of loperamide
« Reply #23 on: September 05, 2010, 12:14:42 pm »
you took too small a dose.

i am about to make me some propionic anhydride, since i cant find it at reasonable prices, and its easy to make.

did you get it or make it?
his pants will be crusted with semen from constantly jerking off whenever he can't find a rape victim.

in the words of archimedes - give me a lever and a place to put it... or i shall kill a hostage every hour.

Offline Dr. Toxicophilous

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Re: propionic/acetic anhydride esterification of loperamide
« Reply #24 on: September 05, 2010, 01:32:16 pm »
Now, for ibogaine esterification!  :-P

Leave those opies alone man. You just went through all that stuff to not touch them!  :-*
Perplext no more with Human or Divine,
To-morrow's tangle to the winds resign,
And lose your fingers in the tresses of
The Cypress-slender Minister of Wine.
-Omar Khayyam

><((((º>`·.¸¸.·´¯`·.¸.·´¯`·...¸><((((º>
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Offline tryl

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Re: propionic/acetic anhydride esterification of loperamide
« Reply #25 on: September 05, 2010, 04:37:41 pm »
Now, for ibogaine esterification!  :-P

Leave those opies alone man. You just went through all that stuff to not touch them!  :-*

no, no, no.

i just CANNOT not try this.

just for the fuck outta it.

just to see if it REALLY works that incredibly good.

plus, after all that stuff, i got more than just clean. the reasons behind me being a junkie in the first place are cleared, solved and left behind. i feel so good, healthy and euphoric, i don't really need opiates. but that doesn't mean i have permanently scratched them off the list and wont ever touch an opiate again. i just now have a sense of control.
« Last Edit: September 05, 2010, 05:03:29 pm by trylobeet »
his pants will be crusted with semen from constantly jerking off whenever he can't find a rape victim.

in the words of archimedes - give me a lever and a place to put it... or i shall kill a hostage every hour.

Offline plantmanbee

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Re: propionic/acetic anhydride esterification of loperamide
« Reply #26 on: September 05, 2010, 06:23:36 pm »
jesus fuck trylo!  :-X  :|

have at it then
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Offline Dr. Toxicophilous

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Re: propionic/acetic anhydride esterification of loperamide
« Reply #27 on: September 05, 2010, 11:12:01 pm »
You're just self justifying, you know that, right?  :wink:
Perplext no more with Human or Divine,
To-morrow's tangle to the winds resign,
And lose your fingers in the tresses of
The Cypress-slender Minister of Wine.
-Omar Khayyam

><((((º>`·.¸¸.·´¯`·.¸.·´¯`·...¸><((((º>
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Offline tryl

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Re: propionic/acetic anhydride esterification of loperamide
« Reply #28 on: September 05, 2010, 11:28:32 pm »
You're just self justifying, you know that, right?  :wink:

no.
just curious.
if i wanted an opioid high, there's plenty of heroin and methadone around, within a hands reach.
« Last Edit: September 05, 2010, 11:32:15 pm by trylobeet »
his pants will be crusted with semen from constantly jerking off whenever he can't find a rape victim.

in the words of archimedes - give me a lever and a place to put it... or i shall kill a hostage every hour.

Offline jc

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Re: propionic/acetic anhydride esterification of loperamide
« Reply #29 on: September 07, 2010, 06:11:09 am »
I acquired it from a top secret location.  You really dont think I took enough?
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