November 22, 2014, 10:55:21 pm

Author Topic: possible recreational use of olanzapine  (Read 1783 times)

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Offline technoboy

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  • Posts: 5
possible recreational use of olanzapine
« on: March 27, 2002, 07:35:00 am »
hello.
i have a (very expensive) box of zyprexa (olanzapine), its a pill for psychotic disorders.
do you know any recreational use of it?

thanks

Offline JDude2

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possible recreational use of olanzapine
« Reply #1 on: March 27, 2002, 07:51:00 am »
Sounds like some pretty serious stuff....

Doesn't sound  too fun though, DA 5-HT antagonist.... yikes

From RXlist:


DRUG ABUSE AND DEPENDENCE

Controlled Substance Class: Olanzapine is not a controlled substance.

Physical and Psychological Dependence: In studies prospectively designed to assess abuse and dependence potential, olanzapine was shown to have acute depressive CNS effects but little or no potential of abuse or physical dependence in rats administered oral doses up to 15 times the maximum daily human dose (20 mg) and rhesus monkeys administered oral doses up to 8 times the maximum daily human dose on a mg/m2 basis.

Olanzapine has not been systematically studied in humans for its potential for abuse, tolerance, or physical dependence. While the clinical trials did not reveal any tendency for any drug-seeking behavior, these observations were not systematic, and it is not possible to predict on the basis of this limited experience the extent to which a CNS-active drug will be misused, diverted, and/or abused once marketed. Consequently, patients should be evaluated carefully for a history of drug abuse, and such patients should be observed closely for signs of misuse or abuse of olanzapine (e.g., development of tolerance, increases in dose, drug-seeking behavior).
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