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 The Lycaeum Forums » Psychedelics & Non Visionary Related » Non Visionary Plants (Moderators: gorfehttimrek, Papyrifera, Noman)Topic:
 Simple Question: Do variant strands of marijuana produce different effects?

[Mens Rea]

If so, would it be safe to say that different types of alcohol (vodka, gin, tequila, wine, etc.) produce different buzzes?

What are the effects from different strains attributed to? If it's eventually just consumption of THC in the end, then how does that even work?

[WeeDie]

I think there's a lot of differences between different strains of marijuana, and different qualities of haschich.

I believe, If you inject someone with pure THC, they will have a blunt sort of trip. While if you inject someone with a combination of THC and other cannabinoids, they will laugh and have fun. THC is just the main ingredient, but it synergizes with different compounds to produce different kind of trips.

I believe the difference in buzz is far greater then the difference between different kinds of alcoholic beverages.

[u]

So, basically you're too lazy to read the lycaeum cannabis page, and you want some kind of summary?

[3lbs]

If so, would it be safe to say that different types of alcohol (vodka, gin, tequila, wine, etc.) produce different buzzes?

while different alcohols and mj strains produce different effects, it's for entirely different reasons. not sure why you'd compare them.

[Noman]

So, basically you're too lazy to read the lycaeum cannabis page, and you want some kind of summary?

Maybe she wants to have a conversation about it rather than rereading old threads.

[foreward]

^^ agree. I dunno why people are so hard on crystal - well - maybe I do know, but for fuck's sake, this is a legitimate enough topic... Besides, if we weren't wasting time already why would we be on the internet? Isn't that the whole point?

Anyway, I am by no means a connoisseur of anything, pot, beer, wine, booze... However, I do know that there are definite difference between the bud I've smoked, and not just in intensity or indica/sativa stereotypes. Pot can range from just mellow to giggly to full blown psychedelic depending on where I get it from.

As for alcohol, I deff agree that any differences are entirely unrelated to pot, however, drink a bottle of wine and compare it to a few shots of vodka. I think anyone will tell you that one differs considerably from the other. Tequila and Fernet Branca are yet another story.

Now ... WTF is up with "evil big box store" DXM tablets? Are they "dirty" or does all the corporate bad mojo become infused with the tablets leading to intense stomach cramping and horrible experiences?

[u]

I gave feedback on the retarded way that she starts topics. It's better than just being "politically correctly polite".

[pshmell]

Crystal, excellent question! I've often wondered that, having heard so many name-brand strains.

I think that it's definitely possible for different strains to produce different effects, insofar as different strains contain different amounts of the various and numerous types of cannabinoids.

For example, check out this video of a study done by the BBC, comparing pure THC high to pure cannabidiol high:
<a href="http://www.youtube.com/v/T2cAFRAX3Gs&amp;hl=en&amp;fs=1&amp;" target="_blank">http://www.youtube.com/v/T2cAFRAX3Gs&amp;hl=en&amp;fs=1&amp;</a>

Here's a page that lists some qualitative effects of different types of cannabinoids: http://www.a1b2c3.com/drugs/mj028.htm

From that page:

CBD (Cannabidiol) increases some of the effects of THC and decreases other effects of THC. High levels of THC and low levels of CBD contribute to a strong, clear headed, more energetic high.

CBN (Cannabinol) is produced as THC ages and breaks down, this process is known as oxidization. High levels of CBN tend to make the user feel messed up rather than high.

If you are a grower, you can experiment with different strains of cannabis to produce the various qualities you seek. A medical user looking for something with sleep inducing properties might want to produce a crop that has high levels of CBD.

Another user looking for a more energetic high will want to grow a strain that has high levels of THC and low levels of CBD. In general, Cannabis sativa has lower levels of CBD and higher levels of THC. Cannabis indica has higher amounts of CBD and lower amounts of THC than sativa.

Wikipedia also has decent articles on almost a dozen different cannabinoids: http://en.wikipedia.org/wiki/Cannabinoid

u, cheer up! When you make other people feel good, you'll feel good too!
Teachers are the happiest class of people I know of!

[u]

Any more brave young know-it-all men that want to do more research for our poor and helpless little girl?

[Papa Doobie]

Only personal research, since it's can't be posted on wikipedia 
Anyone that's ever smoked weed more than once should be able to tell you that different kinds can affect you quite differently. I think set/setting also plays a big part with weed: whether you're getting skullfucked with a few friends on your bong at home, or smoking a blunt with a ton of random people, can, IME, totally affect how you feel. Potency matters too - try smoking headies, then smoking enough outdoors and try to get as high off that as the headies. you may still be equally BAKED, but the feeling will have a different atmosphere and comedown.

[Mens Rea]

So, basically you're too lazy to read the lycaeum cannabis page, and you want some kind of summary?

God, you're a baffoon who obviously can't read between the lines. I'm obviously protesting (without trying to be blatantly offensive or contradictory) of the claim that different strands of weed are capable of producing different effects, because I think it is quite possibly more placebo than anything. There has never been any empirical, concrete evidence aside from PERSONAL EXPERIENCE to support the fact that the effects of marijuana strains are so different. If it were then science experiments would recognize each strain as its own individual drug to test. Hence why I am asking for the PERSONAL EXPERIENCES of the people to formulate their opinion.

For a scientist, you sure have a lot of trouble figuring the most simpleton shit out. On the other hand, you truly are a typical scientist. You fail to grasp that which is not bluntly stated and oversimplified. Next time, I'll help you out and post a bigass sign to help convey the true message of my words:




Now THAT'S being politically correct polite!  

[u]

That was soooooooooooo far away from being obviously anything else except dumb.

But now that you have said something of any substance, let's go through those ideas. What do you think about the fact that there are various psychoactives in cannabis? It's highly likely that there is genetic polymorphism in the biosynthesis pathways of the various plants (means that the different strains aren't genetically identical, and make differnet amounts of different cannabinoids)... it's even possible to breed plants that do not make anything psychoactive at all. Not to mention GM. I don't understand your point about various strand being separate drugs at all. Drug tests try to show that a person has used an illegal substance. If there are different amounts of various cannabinoids in the various strains, but all have THC, then testing for THC metabolites can show use, no? You also claim that there is no scientific evidence that different strains could have different effects. What do you then think about the video in this thread? It may be poor, it may not directly address the question, but it is something isn't it?

You say that I have a problem understanding the most simpleton shit, when you completely retrospectively fabricated your posts intention and content... LMAO!!! Yeah, us scientistamers realliez doesn gets it... You gotta learn to accept people that are not like you.

How bout you use this sign instead:

[Mens Rea]

But now that you have said something of any substance, let's go through those ideas. What do you think about the fact that there are various psychoactives in cannabis? It's highly likely that there is genetic polymorphism in the biosynthesis pathways of the various plants (means that the different strains aren't genetically identical, and make differnet amounts of different cannabinoids)... it's even possible to breed plants that do not make anything psychoactive at all. Not to mention GM. I don't understand your point about various strand being separate drugs at all. Drug tests try to show that a person has used an illegal substance. If there are different amounts of various cannabinoids in the various strains, but all have THC, then testing for THC metabolites can show use, no? You also claim that there is no scientific evidence that different strains could have different effects. What do you then think about the video in this thread? It may be poor, it may not directly address the question, but it is something isn't it?

There we go. Now was that so difficult to post some pertinent information to the thread? FYI from next time, you ought to be using your time constructively in this fashion instead of derailing threads like this, out of an abhorrent distaste for somebody simply because of an asinine joke they made. Don't you think that's much better instead of choosing to withhold credible information hostage in a fallible pretentious attempt of showery? You can ignore me of course--I'm just a wee little member with no modship power. Anyway, class just started, so I gtg. I'll be back to watch the video.

[u]

I'm going to ignore you then. I mean when you ask questions about things that are basic shit that is posted on erowid or the LEDA, it makes one wonder what in the hell is the purpose of me or some one else copy pasting that here for you? That's a total waste of time and lowers the quality of the info and discussion here. IMHO, of course.

Or maybe just in the name of equality I will comment in your future posts that I think that you should UTFSE. I mean you have the right ask dumb shit. But I also have the right to say UTFSE.

We have quarreled over similar issues many times, and I hope you don't think that I want to be mean to you. I just think that it's rude to post on an internet forum without UTFSE fist. Kinda like talking on your cell phone loudly in the library. Not a crime or anything serious, but sure as shit will not make people happy, as in "oh, how thoughtfull of you, you shouldn't have".

[ST1R]

I think that it's definitely possible for different strains to produce different effects, insofar as different strains contain different amounts of the various and numerous types of cannabinoids.

Thats absolutely correct. The subject different effects of various strains(etc) are due to varying amounts of the various cannabinoids as well as set and setting. Indica strains are typically more sedating while sativa strains are usually more energizing. That of course can vary as most plants are blends.

Pure THC is honestly quite dull. I have eaten an ungodly amount of marinol and without a few hits of ganja they are near worthless (for me I have kind of a tolerance ).

Now off topic wtf is up u?
If yer not bitching at bio for no reason you are doing it to CG.
Ego feelin kinda low?

[foreward]

I agree. It's about time someone told u just where to put his fucking search engine. I've got no problem with u personally, but just telling people to basically use a search engine and stfu simply doesn't help anyone. If you don't want to get into something then just don't reply.

[u]

Some people enjoy quality over quantity. People here bost that we are better than drugs forum because we have quality. Uhm, yeah, instead of making a quality report on marinol vs. cannabis and refering to it, better have the same story in 3 lines in 10 000 posts... yeah, let's even let go of the oldest of internet etiquette "search before post". Jesus. You know, Moloko is right when he says that this place has too much overhead and completely useless today. If this is supposed to be one big chit chat, why not use irc? at least the shit wont be permanently saved somewhere. Think about that question for real. How much of the info here really needs to be saved? maybe 0.1%? Maybe not even that? Why not use the chat link? It's quicker...

[ST1R]

You know, Moloko is right when he says that this place has too much overhead and completely useless today.

Then please don't hesitate to fuck off and leave the board to those that love it.

[3lbs]

other things ignored -

Do variant strands of marijuana produce different effects?

Yes. Depending on the strain, and how the plant was grown, it can have varying amounts of different cannabinoids. Ignoring how other cannabinoids have a synergistic action WITH thc, other cannabinoids are psychoactive on their own, so yes.

If so, would it be safe to say that different types of alcohol (vodka, gin, tequila, wine, etc.) produce different buzzes?

No, it's not to safe to say different types of alcohol produces different buzzes BECAUSE different strains of marijuana produce different effects.

However, different types of alcohol have different ingredients, esters, polyphenols, hops, alcohol concentration, impurities, and other additives, all of which can change the buzz.

[Mens Rea]

OK, now I have a short break to dissect this issue.

But now that you have said something of any substance, let's go through those ideas. What do you think about the fact that there are various psychoactives in cannabis? It's highly likely that there is genetic polymorphism in the biosynthesis pathways of the various plants (means that the different strains aren't genetically identical, and make differnet amounts of different cannabinoids)... it's even possible to breed plants that do not make anything psychoactive at all. Not to mention GM. I don't understand your point about various strand being separate drugs at all. Drug tests try to show that a person has used an illegal substance. If there are different amounts of various cannabinoids in the various strains, but all have THC, then testing for THC metabolites can show use, no? You also claim that there is no scientific evidence that different strains could have different effects. What do you then think about the video in this thread? It may be poor, it may not directly address the question, but it is something isn't it?

But that's precisely what my question is about! You assert that there are disparaging amounts of THC in varying strands of cannabis. In this sense, it could be said to be analogous to alcohol with all the different proofs or percentages of alcohol, which is why I mentioned this. But to me, amount is just that--an amount, and doesn't "truly" alter the effects of drugs. Drunk is drunk, no matter what kind of alcohol is imbibed.

I suppose (like foreward said), I HAVE noticed subtle differences in different types of alcohol or cannabis. But, I have also noticed subtle differences from the same exact batch, depending on the day of the month and the time of the day and how I am feeling. (Ever notice how the same batch of MDMA can produce vastly different effects on you when taken at different times of the year?) So I am wondering if it these perceived changes are more attributed to hormonal changes or physiological reactions, rather than the actual batch. These are the disputed differences I wish to receive feedback about.

If the differences of these cannabinoids are recognized scientifically (and if they are as different as say isomers), then how come these specifics aren't stated in any research experiments that I've seen (it's usually just stated as "THC")? This would indicate that the active compound is in fact, the same--which leaves the ubiquitous differences to be either due to individual physique or from inactive ingredients in the marijuana.

I mean, I have heard plausible reasons about why the Marinol compound is synthetically different from smoked marijuana, but we're referring to alleged statements such as "Sativa helps you sleep at night" or "Trainwreck has more of a body high."

I'm going to ignore you then.

Not to be self-defeating, but yes, that would be better than posting defacing belittlements three or four times in a 10-post thread. I mean, now you're just being a troll.

[gorfehttimrek]

Everyone it seems take turn "being the Troll".  I'm sorry, and surprised, that I have to agree with Crystal G's last sentence.  Every post here that one might want to read for its content and information is "infested" with at least one person with an attitude and a keyboard to hit us all over the head with.

SOMETHING is always wrong with SOMETHING around here and SOMEBODY never fails to show up and publicly air the dirty laundry for the rest of us.   

A virtual who's who of petty egoed, panty waisted wordsmiths, willing to say whatever it takes to totally derail the topic of the moment.

Congratulations fucktards... You've DONE IT!  I'm convinced!



Drugs are Bad!  Just say no to Drugs.     Need proof?  Just do a little reading here my friend.  Do a little reading.

[foreward]

My feeling is that the convo starts with the post. If you can't make something interesting from it, then just don't reply. If everyone followed this, then useless threads just would just dissipate into the depths of the lycaeum.

But what we don't need are arrogand post-grads condescending people of "lesser" education.

[Papa Doobie]

anyway, if anyone remembers the original topic...

one of the reasons a varying amount of THC in cannabis vs. differing amts of alcohol in vodka, rum, beer, what have you, makes more of a difference here because THC is not the only active ingredient. Other active ingredient levels (cannabidol etc.) will affect the high also, along with how they interact with THC. this is also part of the reason why you have a legitimate case for medica marijuana rather than just marinol (only thc).

[foreward]

I would maintain though that if you drank the same quantity of alcohol in wine v. vodka, you'll still have different effects, and I think that we have a tendency to overlook different psychoactive elements in various alcoholic beverages for socio-political reasons.

[Carlo]

Totally not a scientist but a huge number of variables affect marijuana plants such as growing mediums, health of mother plant or seedling, quality and length of light exposure, water etc. any or all of which could affect even plants of the same strain when grown in different areas and conditions.

These factors and the range of chemicals occurring in different ratios in each plant are bound to alter the quality of the stone as is the method used to ingest, with differences being even more pronounced between strains.

As has been said, there is quite a difference between Sativa and Indica stones and there are many pure and cross-bred strains enhancing various qualities such as flavour, maturation rates, ideal height and buzz etc.

Set and setting and tolerance levels also play a part.

There's weed that will nail you to the floor and stop conversation, some that will do the opposite and energise you or turn you into a giggling heap and yet others that will cause hallucinations or make you turn grey, break out in a sweat and feel like you're going to faint. Some enhance creativity, others make you forget why you walked into a room or what you were looking for.

Knowing the strain or having some experience with it does seem to give some indication of what to expect.

[b]

LOL @ 1:28.  

Crystal, I've had some true "body buzz" herb before.  Stuff you smoke and you really feel it in your body.  Only once though, and it was real dark; I assume it doesn't come through the states much.  I had some herb butter once a long time ago that we ate just off the skillet in melted form and an hour later my legs were having pulses of "energy" or whatever you want to call it feel like they are going through them.  I haven't been able to get that butter body buzz since then though after many tries... I don't know how/why it happened but it was intense.  We used a mix of shwag and chronic.  

Outside the body buzz stuff, I think most stuff is pretty much the same.  It's only when you find the people with specific strains and lots of know-how that have the shit with the specific effects.  For most average buyers with normal dealers, you might have a hard time getting something with truly specific effects.  It's out there though.  The "elite smokers."  Maybe you Cali potheads have a little better access to them with the whole legalization thing now though...

And damnit, I like it when u tries to pick fights with me.  It keeps me on my toes.

[3lbs]

If the differences of these cannabinoids are recognized scientifically (and if they are as different as say isomers), then how come these specifics aren't stated in any research experiments that I've seen (it's usually just stated as "THC")? This would indicate that the active compound is in fact, the same--which leaves the ubiquitous differences to be either due to individual physique or from inactive ingredients in the marijuana.

There's no reason to conclude differences are minimal and due to an individuals physique, because some studies on thc leave out mention of other psychoactive cannabinoids. There are plenty of studies on these other cannabinoids, and their interplay on THC.

Here's one http://bjp.rcpsych.org/cgi/content/abstract/192/4/306

It is documented that CBD causes sleepiness, and the levels are much higher in indicas, which corresponds to the general response that indicas put you to sleep, more of a body high and sativas can wake you up and has more of a cerebral high. I'm surprised you haven't experienced some of these extremities Cali, because I have found them to be large and very consistent with the indica/sativa leanings of a strain.

[u]

Then please don't hesitate to fuck off and leave the board to those that love it.

LOL, you are really black and white, aren't you? But don't worry I have already been spending more time on the irc than here. And will lessen the time I spend here even more.

Cannabis is a cocktail. Various cannabis strains are various cocktails -> different effects.

Various alcohols are not, in away. They all have only ethanol as the active ingredient. However, the ethanol experience is affected strongly by the rate and extent of alcohol getting to the brain (in scientific terms: the pharmacokinetics of alcohol). So, when you drink shots rapidly, your drunkedness comes about quickly and most people think that it makes you feel energetic and more awake, than if you drink beer slowly for a long time. Of cource most alcoholic drinks contain plants in them, and nearly all plants, especially spices, have subtle psychoactive effects. Alcohol also, in moderate doses, only really affects the GABAnergic neural systems. But at higher concentrations it also acts as an antagonist of the NMDA receptors. You can't really get high blood concentrations with something like beer (this depends on sex, body weight and all that) because it is eliminated constantly. You'd have to down it at the same rate as shots... anyone can down 2-3 shots in under a minute, but do that with pints...

[Mens Rea]

There's no reason to conclude differences are minimal and due to an individuals physique, because some studies on thc leave out mention of other psychoactive cannabinoids. There are plenty of studies on these other cannabinoids, and their interplay on THC.

Here's one http://bjp.rcpsych.org/cgi/content/abstract/192/4/306

It is documented that CBD causes sleepiness, and the levels are much higher in indicas, which corresponds to the general response that indicas put you to sleep, more of a body high and sativas can wake you up and has more of a cerebral high. I'm surprised you haven't experienced some of these extremities Cali, because I have found them to be large and very consistent with the indica/sativa leanings of a strain.

Okay, you posted a really great abstract. I have been worried about whether 4x a week marijuana use would cause me to develop the onset of schizophrenia (again). I hear contradicting reports--some totally dispelling it as myth and others propagating its validity. But, I guess it would be safe to say THC-CBD doesn't? And CBD is like... the indicas? That's so weird you mentioned that, this is primarily what I have been smoking 90% of the time, because it's one of the few strands that causes me to wake up groggy. (Wonder if that's causally related to the schizotypal effects)

One thing I prefer about the sativa-indicas is that I have noticed I wake up the next day with absolutely no hangover effect. It allows me to wake up alert and focused (though not 100% of the time).

[Papa Doobie]

at 4x a week, I think you would have noticed any schizophrenia likely to onset by now, but I'm not a doctor, lawyer, or indian chief.