LINN LS; YAGER J; LEAKE B
Physicians' attitudes toward substance abuse and drug testing.
Int J Addict. 1990 Apr; 25(4): 427-44
Responding to a survey, 303 physicians provided opinions about permissibility of substance use among eight occupational groups, appropriateness of drug-screening programs by employers, and the role of physicians in managing substance abuse problems. The majority felt that neither drugs nor alcohol should be used at lunch by any individuals, but that alcohol and to some degree marijuana use was permissible after work or on weekends. Physicians could not agree about reliability or use of drug-testing programs. However, most believed that employee drug screening was more appropriate after evidence of poor job performance rather than screening all employees or applicants.
STROMBERG, VERNER L
The Isolation of Bufotenine from Pipatdenia peregrina.
Journal of the American Chemical Society; Vol 76 pg 1707 (20-Mar-1954)
The inhalation of a narcotic snuff by the natives of Haiti was a common practice at the time of the discovery of the West Indies. This snuff, called cohoba, was used by the necromancers or priests in their ceremonies and was supposed to enable them to communicate with unseen powers. The ceremonial use of cohoba was described as early as 1496 by Ramon Pane who was with Columbus on his second voyage, but in later years cohoba was confused with tobacco. The chemistry of this snuff has never been studied although the leguminous shrub Piptadenia peregrina is now known to be its source. [1] In the present work there was isolated from the seeds of this plant a crystalline organic base, m.p. 146-147ø, with empirical formula C12H16N2O in 0.94% yield. The ultraviolet absorption spectrum in 0.1 N hydrochloric acid showed a maximum at 295 mæ, a shoulder with a second maximum at 247 mæ. In 0.1 N sodium hydroxide the absorption spectrum shows a shift of the second maximum to 322 mæ. This shift is similar to that observed for the vasoconstrictor 5-hydroxytryptamine (serotonin). [2] A methiodide, picrate, oxalate and m-nitrobenzoate were prepared. The melting points were in good agreement with the literature values for bufotenine. ... The infrared absorption spectrum of the picrate was identical to that of a picrate of a synthetic sample kindly supplied by Dr. M. E. Speeter of the Upjohn Company. The seeds of Piptadenia peregrina evidently comstitute an excellent source of bufotenine. The leaves and branches do not give an alkaloid test with Meyer's or silicotungstic acid reagents. The seed pods give only a slight positive test.
The Yage Letters. William Burroughs and Allen Ginsberg. City Lights Books. copyright 1963. tenth printing 1986. $3.50. ![[ZEFF LIBRARY]](zefftag.gif)
Yager, Joel; Crumpton, Evelyn; Rubenstein, Ralph
Flashbacks among soldiers discharged as unfit who abused more than one drug
The American Journal of Psychiatry v140 p857-61 July 1983
SUBJECTS: Hallucinogenic Drugs and servicemen