AET Abstracts

Some brief snippets from usenet

Newsgroups: rec.drugs.psychedelic
Subject: alpha-ethyltryptamine
Date: 23 Jul 1995 05:58:09 GMT

AUTHOR:  Krebs KM; Geyer MA
 TITLE:  Behavioral characterization of alpha-ethyltryptamine, a
         tryptamine derivative with MDMA-like properties in rats.
SOURCE:  Psychopharmacology (Berl) (QGI), 1993; 113 (2): 284-7

my abstract: Some users report that AET is like MDMA.  The DEA's made it
             schedule I.  Doses of 5, 10, 20 mg/kg in rats increased
             locomotor activity as stimulants and entactogens do and
             hallucinogens don't.  It also decreased investigatory behavior
             as entactogens and hallucinogens do.  Also, pretreatment with
             Prozac lessened the locomotor activity increase.  Therefore AET
             could be an entactogen.


  AUTHOR:  Glennon RA
   TITLE:  MDMA-like stimulus effects of alpha-ethyltryptamine and the
           alpha-ethyl homolog of DOM.
  SOURCE:  Pharmacol Biochem Behav (P3Q), 1993 Oct; 46 (2): 459-62

my abstract: Going from alpha-methyl to alpha-ethyl messes up hallucinogens
             but doesn't affect entactogens too much.  Can alpha-ethyl
             analogs of known hallucinogens DOM and alpha-methyltryptamines
             fool MDMA-trained rats?  They can!  And amphetamine-trained
             rats care for them only somewhat compared to amphetamine, so
             AET and alpha-EH DOM might be entactogens, not just
             stimulants.  Pretty weird stuff.


  AUTHOR:  Huang XM; Johnson MP; Nichols DE
   TITLE:  Reduction in brain serotonin markers by alpha-
           ethyltryptamine (Monase).
  SOURCE:  Eur J Pharmacol (EN6), 1991 Jul 23; 200 (1): 187-90

my abstract: AET is a monoamine releasing agent like MDMA and PCA.  Those
             are somewhat neurotoxic, so maybe AET is too.  Rats were dosed
             eight times with 30 mg/kg subcutaneous AET acetate.
             Investigation of their brains one week later showed decreased
             5-HT, 5-HIAA, and 5-HT uptake sites in the frontal cortex and
             decreased 5-HT and 5-HIAA in the hippocampus.  AET might be
             neurotoxic like MDMA and PCA.


  AUTHOR:  Morano RA; Spies C; Walker FB; Plank SM
   TITLE:  Fatal intoxication involving etryptamine.
  SOURCE:  J Forensic Sci (I5Z), 1993 May; 38 (3): 721-5

my abstract: The original abstract doesn't say much and I haven't tracked
             down the original yet.  Sorry!